Vocabulary Ch7 Flashcards

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1
Q

Drug Information

A

When a provider needs to know drug-related information, the pharmacist goes through a process of referencing a drug information resource. There are many to choose from depending on the specific question that needs to be answered. The pharmacy technician is often asked to find this information for the pharmacist, even though the pharmacist is typically the one who actually communicates the information to the provider, or in some cases, the patient. Accordingly, pharmacy technicians must understand the commonly used drug information resources and must know how to use each one to find the needed information.

1- What are the available strengths of a drug?

2- What are the available dosage forms of a drug?

3- What information is available on drug interactions?

4- What are the possible side effects of a drug?

5- What is the compatibility for the parenteral medications?

6- What are formulas for extemporaneous compounds?

7- What is the cost of the drug and are there any discount programs?

8- Are there off-label usage regulations?

9- Who is the manufacturer and what is its contact information?

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2
Q

General Steps for Using Drug Resources

A

Step1:
Determine which resource has the needed information. This obviously requires knowing the different resource options and the type of information each includes.

Step2:
Look up the drug by using the reference source’s organization system, index, or table of contents. Before you car use the resource, you must know how it is organized. What are the sections, subsections, appendices, chapters, etc.?

Step3:
Locate the needed information and use knowledge of pharmacy and medical terms to interpret this information correctly.
It is essential that you understand pharmacy terminology, drug trade and generic names, and pharmacy basics in order to be able to understand and interpret information in a drug resource.
It is also important to understand basic anatomy, physiology, and disease states.

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3
Q

Drug Resources Organization

A

Most drug resources are organized in one of two ways; by drug name or by drug classification or therapeutic usage.

By Drug Name:

Typically information is organized by both trade and generic names with cross-referencing OR solely by generic name. It is important to know the drug generic and trade name in order to efficiently find drug information in a resource.

By Drug Classification or Therapeutic Usage:

Some resources are organized by how the drug is classified or the drug’s therapeutic usage. Examples include cardiovascular drugs, respiratory drugs, gastrointestinal drugs, etc. Remember, however, that some drugs may be used in multiple systems.

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4
Q

Monographs and Package Inserts

A

One of the most common and easiest ways to access information resource is a drug monograph. This is commonly found in the drug package insert. The FDA requires the drug monograph to be available for any drug in stock. Remember that drug information may change as new information is collected from drug users or the manufacturer. You must ensure you are using current information.

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5
Q

Drug Description

A

The drug description is a written description of the visual elements of the drug and packaging plus the basic chemical structure.

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6
Q

Clinical Pharmacology

A

The clinical pharmacology section provides Information on the drug’s mechanism of action, absorption, distribution, metabolism, elimination, and administration as well as notes about specific patient populations, such as pediatrics.

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7
Q

Indications and Usage

A

The indications and usage information provides specific conditions or symptoms the drug has been approved for prevention and treating by the FDA.

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8
Q

Contraindications

A

The contraindication information includes the types of patients who should not use the medication, such as those with specific conditions (i.e. diabetes) or those taking other medications.

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9
Q

Precautions

A

The precaution information explains all possible or potential side effects the patient might experience while taking the medication.

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10
Q

Drug Abuse and Dependence

A

The drug abuse and dependency information provides a notification in cases where the medication has shown signs of a potential for abuse or dependence.

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11
Q

Adverse Reactions

A

The adverse reaction information explains the reactions that are unexpected and potentially life-threatening for patients who are taking the medication.

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12
Q

Dosage

A

The dosage information provides the recommended dosage of the medication, often categorized by patient age and/or weight. This is especially important with pediatric patients and neonates.

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13
Q

How Supplied

A

This information explains how the medication is supplied, including available strengths, dosage formats, and storage requirements.

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14
Q

Drug Facts and Comparisons Book

A

The Drug Facts and Comparisons reference book is the most commonly used drug information reference. It provides monographs on more than 22,000 prescription drugs and over 6,000 OTC products. The drugs are arranged by therapeutic or pharmacological group. It presents information in text, charts, and tables as well as includes an appendix of treatment guidelines, a list of manufacturers and distributors, and a Canadian trade-name index.

Publisher Information: Drug Facts and Comparison is published by Wolters Kluwer (www.wolterskluwer.com) and updated monthly. It is available as an electronic subscription and via the Lexicomp mobile app. Your pharmacy employer will probably maintain this subscription. With a single search by drug name or NDC, you can connect to a wide variety of drug information databases containing relevant drug knowledge and medication safety content.

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15
Q

Facts and Comparisons eAnswers

A

This online tool provides a modern, updated user interface with intuitive navigation, advanced evidence-based and clinical content, and other essential tools to help retail pharmacies manage their workflow. It is designed to provide quality of content, reduction in medication errors, better patient outcomes, and time saving.

This tool allows you to connect with a wide variety of drug information databases containing relevant drug knowledge and medication safety content:

• A to Z drug facts: A summary drug reference resource

• Off-label drug facts: Assists the healthcare professional in quickly identifying published literature regarding a specific drug use that is not currently approved by the FDA.

•Briggs’ Drugs in Pregnancy and Lactation: The definitive reference on medication use in pregnant and lactating women.

• Risk evaluation and mitigation strategies
(REMS): Provides detailed information on REMS programs as required by the FDA and specified by the manufacturer.

• Medication guides: Created by the manufacturer and approved by the FDA, these guides contain information for patients on how to safely use a medication.

• Natural products database: Provides timely, objective assessment of the latest medical and scientific studies on natural products, including medically active foods, using peer-reviewed monographs.

• Boxed warnings: A reference page containing links to more than 600 Black Box Warnings.

• Manufacturer index: Provides an extensive alphabetical list of manufacturers.

• Don’t crush/chew: Provides an alphabetical list of products that should bot be crushed or chewed.

• Immunization schedules: A resource for routine and special immunization needs for children and adults.

• Patient assistance program information:
Provides information to assist professionals in aiding patients who are having difficulties obtaining their medications.

• Additional information links: Provides links to medically based, qualified websites and primary literature, including other pharmacy reference resources.

• Drug Facts and Comparison, including comparative charts: The electronic Drugs Facts and Comparisons resource, including the comparative charts.

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16
Q

Physician’s Desk Reference

A

The Physician’s Desk Reference (PDR) is primarily used by the provider in the physician’s office. It contains detailed information on more than 1,000 of the most commonly prescribed drugs. It provides detailed product information including chemical information, function/therapeutic action, indications and contraindications, side effects, warnings, and trial research.

Publisher Information: The PDR is published by the PDR Network and is updated annually (www.pdr.net). There is a free PDR app for subscribers from the App Store and Google Play. They no longer publish print books.
Subscribers can use the search tool to The Physician’s Desk Reference (PDR) is primarily used by the provider in the physician’s office. It contains detailed information on more than 1,000 of the most commonly prescribed drugs. It provides detailed product information including chemical information, function/therapeutic action, indications and contraindications, side effects, warnings, and trial research.

Publisher Information: The PDR is published by the PDR Network and is updated annually (www.pdr.net). There is a free PDR app for subscribers from the App Store and Google Play. They no longer publish print books.

Subscribers can use the search tool to search for information by drug name. You can also browse by drug name and search the PDR Drug communications that let’s you review drug alerts, drug recalls, and drug approvals. You can also stay current by following the PDR’s montly Drug Updates and latest FDA news and drug labeling updates. search for information by drug name. You can also browse by drug name and search the PDR Drug communications that let’s you review drug alerts, drug recalls, and drug approvals. You can also stay current by following the PDR’s montly Drug Updates and latest FDA news and drug labeling updates.

17
Q

AHFS Drug Information

A

The American Hospital Formulary Service (AHFS)
Drug Information (AHFS DI) is primarily used in health systems pharmacies and providers. It is a collection of drug monographs for virtually every drug available in the United States. It is arranged by pharmacologic-therapeutic classifications and indexed by trade name, generic name, synonym, abbreviation, pharmacy equivalent name, and former names.

The monograph includes a variety of information.

  • Drug Interactions
  • Adverse reactions
  • Cautions and toxicity
  • Therapeutic perspective
  • Specific dosage and administration information
  • Preparations
  • Chemistry and stability
  • Pharmacology and pharmacokinetics
  • Contraindications

Publisher Information: The AHFS D/ is published by the American Society for Health-System Pharmacists (ASHP) and is developed using an independent, evidence-based evaluation process.
It is available in print, electronic database, and mobile application. The electronic information is updated frequently throughout the year.

The current edition includes information on
COVID-19 vaccines, monoclonal antibodies, and patient management plus other current information and updates.

18
Q

Martindale: The Complete Drug Reference

A

The Martindale: The Complete Drug Reference provides detailed monographs and preparation information on drugs and medicines used throughout the world. It contains over 6,000 monographs that are arranged into 49 chapters based on clinical usage. A major benefit of this resource is its international scope.

This resource contains a variety of information.

  • Standard prescription drugs
  • Investigational and Veterinary drugs
  • Herbal Medicine
  • Pharmaceutical Excipients
  • Vitamins
  • Vaccines
  • Radiopharmaceuticals
  • Contrast and diagnostic agents
  • Recreational and abuse drugs
  • Toxic Substances
  • Disinfectants and Pesticides
  • A directory of around 16,000 manufacturers
  • A multilingual pharmaceutical term index of over 5,000 pharmaceutical terms and routes of administration in 13 major European languages
  • A general Index

Publisher Information: The Martindale: The Complete Drug Reference published by Pharmaceutical Press. It is available in hardback print.

19
Q

USP- NF

A

The USP-NF is a combination of the United States Pharmacopeia (USP) and the National Formulary (NF). It includes more than 4,500 monographs with detailed information on drug identity, strength, quality, purity, packaging, and labeling for substances and dosage forms.
It also contains 230 general chapters that provide step-by-step instructions for assays, tests, and procedures.

Publisher Information: The USP-NF published by the USP and is updated annually. It is available as a digital subscription and via a mobile app.

20
Q

Handbook on Injectable Drugs

A

The Handbook on Nonprescription Drugs provides detailed information on nonprescription drug pharmacotherapy, nutritional supplements, and complementary and alternative therapies. It is used in community pharmacy settings. Chapters cover OTC treatments for numerous conditions.

It is organized by disease-oriented chapters and provides a variety of information.

  • Case Studies
  • Treatment Protocols
  • Comparisons of self-treatment options
  • Patient education boxes
  • Product select guidelines
  • Dosage and administration guidelines

Publisher Information: The Handbook on
Nonprescription Drugs is published by the APh A and is available in print and via online and mobile app access.

21
Q

The FDA Orange Book

A

The Approved Drug Products with Therapeutic Equivalence Evaluations is called the Orange Book or the FDA Orange Book in the pharmacy setting. It identifies drug products approved on the basis of safety and effectiveness by the FDA.

Publisher Information: The FDA Orange Book is published by the U.S. government and is updated frequently. There is an online version that is free to access (www.accessdata.fda.gov).

Using the online tools, you can search for drug information in several ways. You can also find drug patents.
1- Search by Proprietary Name, Active Ingredient, or Application Number

2- Search by Applicant (Company)

3- Search by Dosage Form (for example: Tablet)

4- Search by Route of Administration (for example: Oral)

22
Q

RED BOOK

A

RED BOOK provides product information on more than 200,000 prescription and OTC items, including the latest information on average and wholesale drug costs and pricing.

It provides a variety information.
Publisher Information: The RED BOOK is published by Medical Economics and is updated four times each year. It is published exclusively as an online subscription. (www.publications.aap.org/redbook.com).

1- Nationally recognized average wholesale prices (AWPs), direct prices, and federal upper-limit prices for prescription drugs

2- Direct prices, and federal upper- limit prices for prescription drugs

3- Suggested retail prices for OTC products

4- National drug code (NDC) numbers for all FDA- approved drugs

5- Complete package information, including dotage form, route of administration, strength, and size

6- “Orange Book” codes (FDA-approved drug products with therapeutic equivalent evaluations)

7- Summaries of drug/ food, drug/alcohol, and drug/tobacco interactions.

8- Sugar-free, alcohol-free, lactose- free, galactose-free, and sulfite-containing product listings for customers with special needs

9- A complete list of new molecular entities and generics approved by the FDA

10- Comprehensive manufacturer, pharmaceutical wholesaler, and third-party administrator directories

11- Full-color photographs

12-Vitamin comparison tables (amounts of vitamins and minerals in over 50 popular multivitamin products)

13- Common laboratory values (answers to the most common patient questions about urine sugar levels, cholesterol, blood pressure, etc.)

14- Guide to learning alternative medicine

15- NCPDP billing standards

16- Controlled sus stance inventory sheet

23
Q

The Merck Index

A

The Merck Index is an index of chemicals, drugs, and biologicals. It focuses on the chemical nature and structure of compounds and is used by labs, chemists, and pharmacists

The Merck Manual provides a variety of information.

Publisher Information: The Merck Index is published by Merck and is available in digitally as Merck Index Online.

1- Human and Veterinary drugs

2- Biotech drugs and monoclonal antibodies

3- Substances used for medical imaging

4- Biologicals and natural products

5- Plant and herbal medicines

6- Nutraceuticals and Cosmeceuticals

7- Laboratory reagents and catalyst

8- Dyes, colors, and indicators

9- Environmentally significant substances

10- Food additives and nutritional supplements

11- Flavors and fragrances

12- Agricultural chemicals, pesticides, and herbicides

13- Industrial and specialty chemicals

24
Q

Pediatric and Neonatal Dosage Handbook

A

The Pediatric and Neonatal Dosage Handbook provides 944 drug monographs and resources designed and evaluated specifically for pediatric and neonatal patients. The monographs are arranged alphabetically with up to 40 fields of information each. It also provides more than 100 formulas for extemporaneous pediatric compounds and 290 pages of appendix information. The information is used specifically for dosing regimens, pharmacokinetics, and pharmacodynamics for pediatric patients.

Publisher Information: The Pediatric and Neonatal Dosage Handbook is published by Lexi-Comp and is available in printed editions.

25
Q

Goodman & Gilman’s: The Pharmacological Basis of Therapeutics

A

The Goodman & Gilman’s: The Pharmacological Basis of Therapeutics is used by pharmacists and consists of drug monographs or indices of information that focuses on pharmacokinetics and pharmacodynamics, drug transport, metabolism, pharmacogenomics, and therapeutics.

It categorizes its information into several sections.

1- General Principles
2- Neuropharmacology
3- Modulation of Cardiovascular Function
4- Inflammation, Immunomodulation, and Hematopoiesis
5- Hormones and Hormone Antagonists
6- Drug Affecting Gastrointestinal Function
7- Chemotherapy of Microbial Diseases
8- Chemotherapy of Neoplasticism Devices
9- Special Systems of Pharmacology
10- Appendices

Publisher Information: The Goodman & Gilman’: The Pharmacological Basis of Therapeutics is published by McGraw-Hill and is available in a hardback print edition and via an online subscription.

26
Q

Remington: The Science and Practice of Pharmacy

A

The Remington: The Science and Practice of Pharmacy is a textbook and reference on the science and practice of pharmacy.
It has 133 chapters and covers the full
spectrum of pharmacy practice.

Publisher Information: Remington: The Science and Practice of Pharmacy is published by Elsevier and is available in hardback print and ebook formats.

1- Orientation to Pharmacy Practice
2- Pharmaceutics
3- Pharmaceutical Chemistry
4- Pharmaceutical Testing, Analysis and Control
5- Pharmaceutical Manufacturing
6- Pharmacodynamics
7- Pharmaceutical and Medicinal Agents
8-Fundamentals of Pharmacy Administration
9- Patient Care

27
Q

Micromedex

A

Micromedex is an online and mobile application used by physicians, nurses, and pharmacists. There are many different products each having a unique purpose.

Publisher Information: The Micromedex products are published by Micromedex and are delivered via online and a mobile app.

*Drug Information:
Provides current, accurate, and concise drug, information.

*Disease Information:
Supports disease management with unbiased, evidence-based information and identification of best practices for treating diseases.

*Toxicology Information:
Identifies ingredients for hundreds of thousands of commercial, biological, and pharmaceutical products.

  • Alternative Medicine Information:
    Provides reliable, comprehensive source of referenced, scientifically sound information about complementary and alternative medicine (CAM) therapies and practices.

*Lab Information:
Provides current, accurate, and concise lab information.

*Drug Interactions:
Helps with checking for interacting drug ingredients, their effects, and clinical significance and provides instant access to drug-drug, drug-food, drug-ethanol, and drug-lab test reactions.

*IV Compatibility Tool:
Trissel’s 2 IV Compatibility tool can be used to avoid potentially dangerous drug combination when multiple IV medications are combined.

  • Drug ID Tool:
    Assists in identifying pharmaceutical tablets, caplets, and capsules by any of their physical characteristics such as shape, color, pattern, or imprint code.

*Drug Comparison Tool:
Allows easy access to side-by side drug information.

  • Neofax/Pediatrics:
    Helps clinicians improve outcomes and efficiencies with tools to safely and efficiently prescribe, calculate, and administer drug therapy for neonates and pediatrics.

*Calculators:
Collection of calculators, dosing tools, references, and nomograms. Includes:
• Antidote Dosing and Nomograms
• Dosing Tools
• Laboratory Values
• Clinical Calculators
• Measurement Calculators

*Online Tutorials:
Provides access to numerous training videos and resources

28
Q

Other Resources

A

In addition to these resources, there are numerous drug information resource apps. As a pharmacy technician, it is important to learn how to use the major resources and when each resource can be used to find drug information efficiently. It is also important to be literate in computers and use of online information and resources. Finally, learn how to use the individual apps selected in your place of employment.

Consider exploring these websites online to make sure you understand the type of information that is found on each site as well as how it is organized.

1- Centers for Disease Control and Prevention (CDC)
www.cdc.gov

2- Centers for Medicare and Medicaid Services (CMS)
www.cms.gov

3- Food and Drug Administration (FDA)
www.fda.gov

4- National Institutes of Health (NIH)
www.health.nih.gov

5- National Library of Medicine (NLM)
www.medlineplus.gov

6- U.S. Department of Health and Human Services (HHS)
www.hhs.gov

7- Drugs.com
www.drugs.com

8- Medscape
www.medscape.com

9- Rxlist
www.rxlist.com

10- WebMD
www.webmd.com