vitamins-nutritional pathology Flashcards
What are vitamins?
Organic molecules needed in small quantities for normal metabolism and other biochemical functions, such as growth or repair of tissue. They are essential parts of enzymatic reactions and are found in both plants and animals. Insufficient amounts can lead to various deficiencies.
What are the two main classes of vitamins?
Water-soluble and fat-soluble vitamins.
What are the water-soluble vitamins?
Thiamine (B₁), Riboflavin (B₂), Niacin (B₃), Pyridoxine (B₆), Folate (B₉), Vitamin B₁₂, and Vitamin C (ascorbic acid).
What are the fat-soluble vitamins?
Vitamin A, Vitamin D, Vitamin E, and Vitamin K.
What are the natural sources of Vitamin A?
Beta-carotene from leafy green and yellow vegetables, and retinol from animal dietary products.
What are the indications for Vitamin A supplementation?
Reducing morbidity and mortality in children, treating Vitamin A deficiencies, and treating skin conditions such as acne and psoriasis.
What are the clinical manifestations of Vitamin A deficiency?
Night blindness, bitot spots, conjunctival and corneal xerosis, retinopathy, keratomalacia, hyperkeratosis, and increased morbidity and mortality after bacterial and viral illnesses.
What are the two main forms of Vitamin D?
Vitamin D₂ (Ergocalciferol) and Vitamin D₃ (Cholecalciferol).
How is Vitamin D₃ synthesized?
It is synthesized in the skin by exposure to direct sunlight (ultraviolet B radiation) and from fish liver oils/saltwater fish.
What are the deficiencies associated with Vitamin D?
Osteomalacia in adults (soft bones)
osteoporosis in adults (brittle bones)
rickets in children.
What are the indications for Vitamin D supplementation?
Treating chronic diseases related to Vitamin D deficiency (e.g., rickets, osteomalacia) and preventing osteoporosis.
What is Vitamin E necessary for?
Formation of red blood cells, a healthy circulatory system, and prevention of oxidative damage to cell membranes and tissues. It is a natural antioxidant.
What are the deficiencies associated with Vitamin E?
Hemolytic anemia in infants, muscle weakness (particularly in children), and retinopathy of prematurity in newborns.
What is the indication for Vitamin E supplementation?
Treating Vitamin E deficiency.
What are the sources of Vitamin K?
Various foods high in Vitamin K, such as leafy green vegetables.