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Biochemistry > Vitamins > Flashcards

Vitamins Flashcards

1
Q

What is the active form of Riboflavin ( Vit B2)?

A

FMN- flavin mononucleotide,

FAD- flavin adenine dinucleotide

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2
Q

What is the Active form of niacin ( vitB3) ?

A

NAD+ - nicotinamide adenine di nucleotide

NADP+ - nicotinamide adenine di nucleotide phosphate

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3
Q

What is the Active form of pantothenic acid ( vit B5) ?

A

Coenzyme A

Acyl carrier protein

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4
Q

What is the Active form of pyridoxine (Vit B6) ?

A

PLP- pyridoxal phosphate

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5
Q

What is the Active form of biotin (vit B7) ?

A

Biocytin- enzyme bound biotin

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6
Q

What is the Active form of folic acid (Vit B9)

A

THF- tetrahydrofolic acid

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7
Q

What is the Active form of cynocobalamin (Vit B12)

A

Methyl cobalamin

Deoxyadenosylcobalamin

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8
Q

What is the Active form of ascorbic acid (Vit C)

A

Ascorbic acid

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9
Q

What sources can you get thiamine- Vit B1 from? And what is it’s daily requirements?

A

Cereals, meat, nuts, green vegetables, eggs

1.0-1.5 mg

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10
Q

What sources can you get riboflavin- Vit B2 from? And what is it’s daily requirements?

A

Yeast, germinating seeds, green leafy vegetables, milk, eggs, liver, meat

1.3-1.7 mg

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11
Q

What sources can you get niacin - Vit B3 from? And what is it’s daily requirements?

A

Yeast, legumes, liver, meat

15-20 mg

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12
Q

What sources can you get pantothenic acid- Vit B5 from? And what is it’s daily requirements?

A

Wheat germs, yeast, cereal , liver, eggs

5-10 mg

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13
Q

What sources can you get pyridoxine - Vit B6 from? And what is it’s daily requirements?

A

Yeast, unrefined cereals, pulses, vegetables, meat, fish, egg yolk

1.6-2.0 mg

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14
Q

What sources can you get biotin - Vit B7 from? And what is it’s daily requirements?

A

Liver, kidney, egg yolk, vegetables

150-300 micro g

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15
Q

What sources can you get folic acid - Vit B9 from? And what is it’s daily requirements?

A

Green leafy vegetables, liver, yeast

200 micro g

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16
Q

What sources can you get cynocobalamin- Vit B12 from? And what is it’s daily requirements?

A

Only animal origin: meat, eggs, liver, fish

3 micro g

17
Q

What sources can you get ascorbic acid - Vit C from? And what is it’s daily requirements?

A

Citrus fruits, Amla, leafy vegetables, tomato

60-70 mg

18
Q

What are the functions and deficiency manifestations of thiamine- Vit B1?

A

Oxidative decarboxylation and transketolase reactions

Beriberi - dry (neuritic), wet (cardiac), infantile
Wernicke korsakoff syndrome

19
Q

What are the functions and deficiency manifestations of riboflavin - Vit B2

A

Coenzyme for oxidation reduction reactions

Cheilosis- fissures at the angles of mouth
glossitis- swollen, magenta tongue
dermatitis- rough, scaly skin
vascularisation of cornea

20
Q

What are the functions and deficiency manifestations of niacin- Vit B3

A

Coenzyme for ox-red reactions

Pellagra- dermatitis, diarrhoea, dementia, death

21
Q

What are the functions and deficiency manifestations of pantothenic acid- Vit B5?

A

Acyl carrier

No clear cut case- Burning feet syndrome in war prisoners
Abnormal tingling sensation 
Headache
Dizziness
GI Malfunctiom
22
Q

What are the functions and deficiency manifestations of pyridoxine- Vit B6?

A

Coenzyme for decarboxylation, transamination, non oxidative deamination, trans- sulfuration reactions

Epileptic convulsions, dermatitis, hypochromic microcytic anaemia

23
Q

What are the functions and deficiency manifestations of biotin- Vit B7?

A

Coenzyme for carboxylation reactions

Rare dermatitis

24
Q

What are the functions and deficiency manifestations of folic acid- Vit B9?

A

Carrier of one carbon unit eg. : CH3, CH2, CH, CHO, CH=NH
Synthesis if methionine, purines, pyrimidines

Megaloblastic anaemia, neural tube defects

25
Q

What is the active form of thiamine (Vit B1) ?

A

TPP - thiamine pyrophosphate

26
Q

What are the functions and deficiency manifestations of cynocobalamin- Vit B12?

A

Coenzyme for reactions:
homocysteine to methionine
Methylmalonyl- CoA to Succinyl-CoA

Pernicious anaemia
Megaloblastic anaemia
Neuropathy
Methylmalonic aciduria

27
Q

What are the functions and deficiency manifestations of ascorbic acid -Vit C

A

Antioxidant.
Involved in synthesis of collagen, steroid, hormones, adrenaline etc.
facilitates absorption if iron from intestine

Scurvy

Biochemistry (5 decks)

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