Vitamin K Flashcards
What are some sources of vitamin K?
Lots of Plants:
Spinach
Broccoli
Kale
Brussel Sprouts
Cabbage
Lettuce
Where is vitamin K synthesized?
Bacteria in Colon
How is Vitamin K absorbed and with what other components?
Absorbed as micelle with other lipds
How is Vitamin K transported?
Transported with Chylomicrons
What is the primary function vitamin K is needed for?
Blood Clotting
What clotting factors require vitamin K for normal function?
II (2)
VII (7)
IX (9)
X (10)
What is a secondary function vitamin K is needed for?
Osteoclacin Formation
Osteoclacin formation is the process of _______ of the protein which is involved in ______ turnover/remodeling?
Carboxylation > Bone
What is the most notable issue with vitamin K deficiency?
Hemorrhage (lack of clotting ability)
An additional vitamin K deficiency is?
Osteoporosis
What are some populations at risk for vitamin K deficiency?
Newborns
Fat Malabsorption
Prolonged Antibiotic Use
Why are newborns at risk for vitamin K deficiency?
Sterol Gut: no bacteria present to synthesize
Why is prolonged antibiotics use an issue for vitamin K deficiency?
Synthesis of vitamin K occurs by bacteria in the colon
What is the upper limit for vitamin K?
No Upper Limit
Patients on ______ medications should be intaking less vitamin K.
Anticlotting Medications
How is vitamin K assessed?
Prothrombin Time (speed of clotting)
