Vitamin E

Question 1

Tocopherol is a

Answer 1

lipid antioxidant that removes peroxyl radicals

Question 2

Tocopherol is regenerated by

Answer 2

ascorbate

Question 3

Tocopherol has an

Answer 3

isoprenoid chain (branched chain unsat hydrocarbon)

and a reactive OH group on the ring which becomes an O radical (called lipid peroxy radical)

Question 4

Lipid peroxy radicals are formed in the process of

Answer 4

membrane lipid peroxidation

one of the commonest forms of oxidative damage caused by ROS

Question 5

How is tocopherol inserted into the membranes?

Answer 5

By its isoprenoid chain

it is positioned to enable it to remove lipid peroxyl radicals produced by lipid peroxidation

Question 6

Like ascorbate, humans do not

Answer 6

synthesise Vit E so require it from the diet