Vitamin E

Question 1

Properties

Includes

primary bioactive form is

Answer 1

antioxidant

Tocopherols and tocotrienols

alpha tocopherol

Question 2

Source

O
M
E
N
V

alpha tocopherol in

Answer 2

food- oil/meat/egg/nut/veggies

olive/sunflower oil

Question 3

Alpha tocopherol quantified via

works as

helps to maintain

reabsorption requires

Answer 3

RRR isomer (natural)

free rad scavenger- protecting PUFA (cell membranes) from peroxidation

fluidity of CM

lingual/gastric lipase, bile salt, panc fxn, intestinal/ileal absorption

Question 4

Def

Potential do causing deficiency

child w CF may be deficient, characterized by

abetalipoproteinemia

Answer 4

uncommon, unless severe and prolonged

Celiac, SB resect, bariatric surgery

hemolytic anemia

cannot transport VE

Question 5

CM

no effect at preventing

Answer 5

hemolysis, ataxia, PN, NM do

CV dz/cancer etc

Question 6

Toxicity

high dose (>800)

contraindicated in

normal indiv should avoid

Answer 6

low w normal liver fxn

reduce platelet agg/VK metabolism

warfarin/antiplatelet agents

daily supplements above 400