Vitamin B3 Deficiency - Pellagra Flashcards by Dr. Tonmoy Biswas | Brainscape

Q

What causes Pellagra?

A

Nicotinic acid (Niacin) deficiency

Isoniazid therapy (Anti-TB)

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Q

Clinical triad of pellagra

A

3D

Dementia

Dermatitis

Diarrhoea

If not treated >> 4th D is Death

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Q

How does isoniazid cause pellagra?

A

It inhibits the conversion of tryptophan to niacin

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Q

What are the 3 main features of pellagra?

A

Dementia

Dermatitis

Diarrhoea

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Q

Psychiatric feature of Pellagra

A

Depression

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Q

How does dermatitis of pellagra look like?

A

Brown scaly rash

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Q

Sites of dermatitis in pellagra

A

Sun exposed areas

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Q

What is Casal’s necklace?

A

Brown scaly rash around the neck

(one of the sun-exposed areas)

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Q

Prognosis of pellagra, if not treated

A

Death

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Q

Findings and diagnosis of the pictorial

A

Findings: Casal’s necklace

Diagnosis: Pellagra

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