Vitamin B2 Flashcards
1
Q
a) Vitamin B2 (riboflavin) has isoalloxazine ring which is the reactive part. It is converted to two flavin nucleotides i.e.
b) Vitamin B2 is destroyed by _____ light.
A
a) Flavin mononucleotide (FMN)
Flavin Adenine Dinucleotide (FAD)
b) UV
2
Q
State the sources of riboflavin.
A
- milk
- meat
- liver
- green vegetables
- fish
- eggs
3
Q
State the roles of Vitamin B2.
A
- Class I enzymes i.e. oxido-reductases require FAD as their coenzymes. These are mostly dehydrogenases.
- FMN is present in the Electron Transport Chain (ETC) hence flavin nucleotides are used in energy generation.
4
Q
Outline the outcomes of riboflavin deficiency.
A
- Cheilosis [swelling and fissuring of the lips] and angular stomatitis [a type of sores that appear at the corners of the mouth], dermatitis
- Glossitis: the tongue becomes smooth and purplish
- Note: ariboflavinosis = riboflavin deficiency
5
Q
Which of the following is not a component of FAD?
A. Isoalloxazine ring
B. Ribitol
C. Piperazine
D. Adenine
E. Nicotinic acid
A
Choice E