Metabolism: Gylcolysis Flashcards
Where does glycolysis occur?
cytoplasm of the cell
What happens during the energy investment phase of glycolysis?
During the energy investment phase, two ATP molecules are used to phosphorylate glucose, converting it into two molecules of glyceraldehyde-3-phosphate.
What happens during the energy payoff phase of glycolysis?
During the energy payoff phase, the two molecules of G3P are converted into pyruvate, producing four ATP molecules and two NADH molecules.
What happens during the energy payoff phase of glycolysis?
The first step is the phosphorylation of glucose by hexokinase, using one ATP to form glucose-6-phosphate.
What happens in the second step of glycolysis?
Glucose-6-phosphate is converted into fructose-6-phosphate by the enzyme phosphoglucose isomerase.
What is the third step of glycolysis?
Fructose-6-phosphate is phosphorylated by phosphofructokinase-1 (PFK-1), using one ATP to form fructose-1,6-bisphosphate.
What happens in the fourth step of glycolysis?
Fructose-1,6-bisphosphate is split into two three-carbon molecules: dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (G3P) by the enzyme aldolase.
What is the fifth step of glycolysis?
Dihydroxyacetone phosphate (DHAP) is converted into glyceraldehyde-3-phosphate (G3P) by triose phosphate isomerase.
What happens in the sixth step of glycolysis?
Glyceraldehyde-3-phosphate (G3P) is oxidized and phosphorylated by glyceraldehyde-3-phosphate dehydrogenase, producing 1,3-bisphosphoglycerate and NADH.
What is the seventh step of glycolysis?
1,3-bisphosphoglycerate donates a phosphate group to ADP, forming ATP and 3-phosphoglycerate, catalyzed by phosphoglycerate kinase.
What happens in the eighth step of glycolysis?
3-phosphoglycerate is converted into 2-phosphoglycerate by the enzyme phosphoglycerate mutase.
What is the ninth step of glycolysis?
2-phosphoglycerate is dehydrated by enolase to form phosphoenolpyruvate (PEP).
What happens in the tenth step of glycolysis?
Phosphoenolpyruvate (PEP) donates a phosphate group to ADP, forming ATP and pyruvate, catalyzed by pyruvate kinase.
What is the net yield of ATP and NADH from glycolysis?
The net yield from glycolysis is 2 ATP molecules and 2 NADH molecules per molecule of glucose.