Bioinformatics Flashcards

1
Q

COSMIC database can be used to access information on ________.
(a) somatic mutations and cancer types in humans
(b) nucleotide sequences of microorganisms
(c) drugs used in cancer treatment
(d) genomic data in humans
(e) metabolic pathways of parasites

A

(a) somatic mutations and cancer types in humans

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2
Q

Which of the following is a literature database?
(a) GenBank
(b) European Nucleotide Archive (ENA)
(c) UniProtKB
(d) Online Mendelian Inheritance in Man (OMIM)
(e) None of the above is correct.

A

(d) Online Mendelian Inheritance in Man (OMIM)

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3
Q

You have a known drug and you would like to identify its gene target. Which of the following will be the suitable database for your search?
(a) UniProtKB
(b) EuPathDB
(c) OMIM
(d) Therapeutic Target Database (TTD)
(e) DNA Databank of Japan (DDBJ)

A

(d) Therapeutic Target Database (TTD)

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4
Q

Bioinformatics is ________.
(a) the use of computers and internet
(b) the storage, retrieval and analysis of biological data
(c) the study of biological information
(d) computational techniques for creating biological problems
(e) the science of information

A

(b) the storage, retrieval and analysis of biological data

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5
Q

UniProtKB/TrEMBL;
(a) is a protein sequence database
(b) is a computationally-annotated database
(c) contains translations of coding sequences (CDS) from EMBL (ENA)
(d) is a part of the Universal Protein Resource
(e) all the above choices are correct

A

(e) all the above choices are correct

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6
Q

You would like to establish the correlation between gut bacteria and obesity. Which of
these databases will give you relevant information?
(a) GiardiaDB
(b) ToxoDB
(c) MicrobiomeDB
(d) PlasmoDB
(e) Vectorbase

A

(c) MicrobiomeDB

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7
Q

Basic Local Alignment Search Tool (BLAST)
(a) Is a rarely used bioinformatics protocol
(b) Uses only protein sequences
(c) Uses only DNA sequences
(d) Is a family of programs that carry out different classes of homology search
(e) Is the only homology search algorithm

A

(d) Is a family of programs that carry out different classes of homology search

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