Vitamin Flashcards
Vitamins
-organic compounds
-essential
-noncaloric
some precursors/provitamins
-failure to consume -causes specific
deficiency diseases.
Vitamin: do or don’t:
Provide energy.
DO NOT
Vitamin: do or don’t:
Act as regulators in the metabolism of proteins,
carbohydrates, and fats into energy.
DO
Vitamin: do or don’t:
Serve as components of body tissues.
DO NOT
Vitamin: do or don’t:
Serve as magic bullets of all diseases.
DO NOT
Vitamin: do or don’t:
Act to build and maintain bone, muscle, and red
blood cells.
DO
Vitamin: do or don’t:
Cure the disease caused by their absence.
DO
Thiamin (B1) fat or water soluble?
water
Riboflavin (B2) fat or water soluble?
water
Niacin (B3) fat or water soluble?
water
Vitamin B6 fat or water soluble?
water
Folate fat or water soluble?
water
Vitamin B12 fat or water soluble?
water
Biotin fat or water soluble?
water
Pantothenic fat or water soluble?
Water
Vitamin A fat or water soluble?
Fat
Vitamin D fat or water soluble?
Fat
Vitamin E fat or water soluble?
Fat
Vitamin K fat or water soluble?
Fat
Vitamin C fat or water soluble?
water
Do not dissolve in water?
fat soluble
Require dietary fat for transport in blood?
fat soluble
Excess can be stored in fat tissues of body
fat soluble
Higher potential for toxicity
fat soluble
Dissolve in water
water soluble
Easily transported in blood
water soluble
Excess is excreted in urine
water soluble
Low potential for toxicity
water soluble
Choline: water or fat soluble?
water
Deficiency symptoms develop in a few weeks or months.
Water soluble
Easily destroyed by light, heat, chemicals.
water soluble
Excreted by kidneys if excess.
water soluble
___ stores may last for a year or more.
B12 in water soluble
in water soluble vitamins,
Excess ___, ___, ____ have ill effects.
niacin, B6, and vitamin C
Foods never deliver a toxic dose of them but large doses concentrated in what can cause toxic levels?
some vitamin supplements can reach toxic levels.
Help the body use the energy-yielding nutrients for energy.
Roles in metabolism in B vitamins
Combine with enzyme to activate it and help it do its’ job.
Coenzymes in the b vit in unison
Critical for energy production, especially during exercise.
Coenzymes in the b vit in unison
- Every cell is affected
- Rarely are isolated deficiencies
- Swollen, smooth tongue
- corners of mouth are inflamed and cracked
Vitamin B deficiency
Thiamin also known as?
B1
Functions:
- Energy production
- Nervous system
B complex: Thiamin
-RDA: -Men = 1.2 mg -Women = 1.1 mg or -0.5 mg/1,000 kcal expended
B-Complex Vitamin: Thiamin
Signs of deficiency: -Headaches -Confusion -Muscle pain and weakness -Fatigue -Beriberi in severe cases
Thiamin
Symptoms of toxicity:
-Toxic buildup is rare
-UL not established
Thiamin
Also known as B2
Riboflavin
Function is Electron transport in aerobic energy production
Riboflavin
RDA:
Men = 1.3 mg
Women = 1.1 mg
Riboflavin
Signs of deficiency:
-Red, cracked lips
-Sore throat
-Inflamed tongue
Riboflavin
Symptoms of toxicity:
-Toxic buildup is rare
-UL not established
Riboflavin
Also known as B3
Niacin
Can be formed from tryptophan: 60 mg tryptophan equivalent to 1 mg niacin (NE)
Niacin
Functions:
-Electron transport in aerobic and anaerobic energy production
Niacin
RDA:
-Men = 16 mg
-Women = 14 mg
Niacin
Signs of deficiency: -Skin rashes -Mental confusion -Muscle weakness -Fatigue -Pellagra in severe cases (3 D’s; UnTx=4th D)
Niacin
Symptoms of toxicity: -Itchy rashes -Headaches and nausea -Liver complications -UL = 35 mg
Niacin
Are supplements needed for Niacin?
- Not recommended for athletes:
- High doses: deplete glycogen stores/block FFA release from adipose tissue; decrease heat storage/increase blood flow to skin.
- Several pyridox forms
- Important for health and athletic performance.
B6
RDA:
-Men and women =1.3 mg
B6
Functions:
-Component > 100 enzymes
-Glycogen for energy and gluconeogenesis
-Transamination: produces AA endogenously so not all need to be consumed through the diet.
-Conversion of tryptophan to niacin
-Formation of neurotransmitters: important for fine motor control/movement in sport.
-Production of RBC’s hemoglobin ring-essential in endurance activity relying on oxygen.
-Production of WBC’s
-Protection from heart disease (with B12 and folate) –low intake -increased homocysteine levels.
B6
Signs of deficiency:
-Deficiencies rare
-Symptoms include nausea, convulsions, skin disorders, fatigue, weakness, anemia
B-Complex Vitamin: B6
Symptoms of toxicity:
-Impaired gait
-UL = 100 mg
-Irreversible nerve damage (1000-2000 mg/d)
B6
are B6 supplements needed?
increased protein intake may need more
Also known as
cobalamin
B12
Functions: -Energy production -Tissue growth and development -Nervous and cardiovascular health
B12
RDA:
Men and women =
2.4 μg
B12
Signs of deficiency: -Deficiencies develop slowly -High homocysteine -Neurological problems -Pernicious anemia
B12
Symptoms of toxicity:
-Toxicity is rare
-UL not established
B12
Are supplements for B12 needed?
Vegetarian or masters/elderly athletes
Also known as folic acid
Folate
Functions: -DNA synthesis -Cell division (e.g., neural tube defects) -Tissue repair -RBC maturation
Folate
RDA:
Men and women =
400 μg
Folate
Signs of deficiency: -Neural tube defects -Macrocytic anemia -Chronic diarrhea -Impaired immune function
Folate
Symptoms of toxicity:
-Toxicity is rare
-UL = 1,000 μg
Folate
Are folate supplements needed?
women of childbearing age
Functions:
-DNA synthesis
-Aerobic energy production from
CHOs, fats, proteins
Biotin
AI:
No RDA
AI for men and women = 30 μg
Biotin
Signs of deficiency: Deficiencies are rare Depression Dermatitis Fatigue Nausea
Biotin
Symptoms of toxicity:
None documented
UL not established
Biotin
Functions: Aerobic energy production from CHOs, fats, proteins
Pantothenic acid
AI:
-No RDA
-AI for men and
women = 5 mg
Pantothenic Acid
Signs of deficiency: Sleep disturbances Impaired coordination Muscle cramping Fatigue Nausea
Pantothenic Acid
Symptoms of toxicity:
None documented
UL not established
Pantothenic Acid
Muscle activation (neurotransmitter-acetylcholine) Structural integrity of cell membranes
Choline
Where does Choline come from?
Wide variety of foods (egg yolks, nuts, milk,
wheat germ, etc)
Made endogenously from methionine
AI:
No RDA
AI = 550 mg (men) and 425 mg
(women)
Choline
Deficiencies in Choline are rare?
True
Symptoms of toxicity: Low blood pressure Diarrhea Fishy body odor UL = 3,500 mg
Choline
Are supplements needed for Choline?
Equivocal results: increase fat oxidation
during exercise and decrease fat mass
Also known as Ascorbic acid or
ascorbate
Vit C
Functions:
Collagen synthesis
Immune function
Antioxidant
Vit C
RDA:
Men = 90 mg
Women = 75 mg
Smokers = +35 mg
Vit C
Signs of deficiency:
Swollen gums
Fatigue
Scurvy
Vit C
Symptoms of toxicity: Relatively nontoxic Kidney stones Nausea and diarrhea UL = 2,000 mg
Vit C
WATER SOLUBLE VITAMIN
DEFICIENCY: Step 1
VITAMIN DEFICIENT DIET:
Tissue level slowly declines
WATER SOLUBLE VITAMIN
DEFICIENCY: 3-4 weeks?
BIOCHEMICAL LESION:
- Enzyme activity decreases
- General sx’s of deficiency
WATER SOLUBLE VITAMIN
DEFICIENCY: 6-8 Weeks
CLINICAL LESION
Outward signs of deficiency
Also known as retinoids
Vitamin A
Functions: Vision Cell differentiation Immune function Antioxidant
Vit A
RDA: Men = 900 μg RAE Women =700 μg RAE
Vit A
Signs of deficiency:
Deficiencies are rare
Night blindness
Hyperkeratosis
Vitamin A
Symptoms of toxicity: Vomiting Fatigue Blurred vision Liver damage UL = 3,000 μg RAE
Vitamin A
Do you need vitamin A supplements?
Not recommended, food is a better source
Compounds found in plants
Not considered vitamins
Carotenoids
Some carotenoids can be converted into vitamin A:
-Provitamin A carotenoids-precursor to
vitamin A: beta-carotene
-Non-provitamin A carotenoids: lycopene,
lutein, zeaxanthin
Functions:
Antioxidant
Immune function
Carotenoids
RDA/AI:
No RDA/AI established
Carotenoids
Intake of carotenoids can be increased by consuming:
5–9 servings of fruits and vegetables daily Colorful fruits and vegetables Drinking 100% fruit or vegetable juice
Excess _____ is stored in fat
under the skin, imparting a yellow cast.
beta-carotene
Also known as Sunshine” vitamin
Vitamin D
Functions: -Controls blood calcium levels -Bone growth/ development
Vitamin D
RDA for men and women:
RDA (19-70 yo)= 600 IU
RDA (70+ yo) = 800 IU
Vitamin D
Signs of deficiency:
Rickets
Osteoporosis
Vitamin D
Symptoms of toxicity: Hypercalcemia Muscle weakness Heart arrhythmias Kidney stones UL = 50 μg
Vitamin D
Are supplements needed for Vitamin D
Blood test, indoor activity,
inadequate calories or low Vit D
food choices
Also known as
alpha-tocopherol
Vitamin E
Functions:
Antioxidant
Vitamin E
RDA (alphatocopherol):
RDA for men and
women = 15 mg
Vitamin E
Signs of deficiency: Deficiencies are rare Muscle weakness Loss of motor coordination Hemolytic anemia
Vitamin E
Symptoms of toxicity:
Decreased blood clotting
Easy bruising
UL = 1,000 mg
Vitamin E
Belong to the
quinone family of
compounds
Vitamin K
Functions:
Blood clotting
Bone
mineralization
Vitamin K
AI:
Men = 120 μg
Women = 90 μg
Vitamin K
Signs of deficiency:
Impaired blood clotting
Excessive bleeding
Vitamin K
Symptoms of toxicity:
None documented
UL not established
Vitamin K
What are the 3 Antioxidant Vitamins:
Beta-carotene , Vitamin E, and Vitamin C
Prevent or repair damage to cells caused by ______
free
radicals.
A free radical forms when hydrogen or oxygen ____ __ _____
loses an electron.
Atoms and molecules that have lost electrons to
free radicals are said to be ______
oxidized
_____ _______are reactive and damage cell
membranes, DNA, and other cell components.
Oxidized substances
_________ stabilize oxidized molecules or repair
them.
Antioxidants
Chemical substances from plants
phytochemicals
Approximately __ phytochemicals are
consumed in a typical American diet
50
Consumption is associated with
decreased risk for:
cardiovascular
disease and cancers
Common sources of what are fruits, vegetables,
and grains?
phytochemicals
- Group of varied phytochemicals
- Antioxidant properties
- Protect against cardiovascular disease
Phytochemicals:
Phenolic Compounds
Most common examples:
Flavonoids
Phenolic acids
Phytochemicals:
Phenolic Compounds
Sources of phenolic compounds?
Grapes (wine)
Teas
- Group of phytochemicals
- Anticancer agents
Phytochemicals: Organosulfides
Examples:
Glucosinolates
Indoles
Isothiocyanates
Phytochemicals: Organosulfides
sources of Organosulfides:
Cruciferous (brassica) vegetables
Garlic
Onions
Classified as a carotenoid
Antioxidant and anticancer agents
Phytochemicals: Lycopene
Sources of Lycopene:
tomatoes and tomato products
Tips for Increasing
Phytochemical Intake
Serve hot or cold green tea with meals
Keep red or green grapes washed and
ready in the refrigerator for snacks
Use tomato sauces, pastes, and
spaghetti sauce as a basis for meals
Sprinkle nuts and seeds on salads
Use garlic in cooking, dressings,
marinades, and sauces
Tips for Increasing
Phytochemical Intake
Use soy milk instead of dairy milk on cereal or as a beverage Complement all meals with one or two fruits or vegetables Use whole grain foods more often than processed grains Try a new grain recipe that uses bulgar, barley, or oats Eat fruit for dessert such as a baked apple, chopped melon, or chilled berries
7 valid reasons for taking supplements
Nutrient deficiency Medical need Prenatal/pregnancy Lactose intolerant Habitual dieters Elderly Strict vegetarian/vegan (riboflavin, B12, calcium, iron, zinc, Vit D)