Visual Cortex Flashcards
describe why certain tracts cross at the optic chiasm
nasal retinal tracts decussates, temporal do not
ganglion cells in temporal retina express Eph B1 and optic chiasm cells express Eph B2, and those two signals repel each other
nasal retina ganglion cells dont express Eph B1, so there is no repulsion
optic radiation
projections from lateral geniculate
2 routes
above calcarine sulcus- upper retinal quadrants and lower visual field
below calcarine sulcus (meyers loop) - lower retinal quadrants, upper visual field
point to point projection
there is point to point projection from retina thru the lateral geniculate and to the visual cortex
on the retina, the image is inverted top to bottom and left to right
monocular blindness
disease or damage of one of the eyeballs or of the optic nerve and loss of the visual field
anopsias
large field deficits
bitemporal hemianopsia
loss of info from temporal visual fields
homonomous hemianopsia
loss of vision in half of a visual field, same visual field in each eye is lost
ocular dominance columns
arrangements of vertical columns w/ cells receiving input from a small piece of retina in one eye adjacent to cells receiving input from that same piece of retina in the other eye
hypercolumn- left and right ocular dominance columns together
BLOBS
cells interspersed among the columns that process color info w/o orientation specificity
laminar organization in V1
LGN input goes to layer 4, which projects to 2/3, then down to 5/6
layers 2/3 project to visual association layers
development of topographic organization in V1
ephrins and eph gradients guide inputs from LGN to v1
abnormal ocular dominance
if one eye is neglected, thinner ocular dominance columns result
critical period where there is plasticity to develop cells that have duel input from both eyes
can result in cortical blindness
strabismus
misalignment of the two eyes
causes more “individualy driven” cells in the cortex rather than cells that receive input from both eyes
esotropia- cross eyed
exotropia- divergent strabismus
amblyopia
“lazy eye”- brain ignores input from eye
both chemical cues (ephs/ephrins) and coordinated electrical activity is required for ocular dominance columns
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