Viruses and Cancer Flashcards
How many cancers were caused by infectious agents in 2008?
2M out of around 12M
What are classed at the group 1 carcinogen infectious agents?
eBV, KSHV, Hepatitis C and B, Human T cell Lymphotopic, HIV1, Human papillomavirus HPV16,18 and the other high risk types
What are the Bacterial Group 1 Carcinogens?
Helicobatcer Pylori
How many cancers in Saharan Africa are caused by viruses and how many are Austrailia?
A 33.3% Third but in Austrailia 3.3%
Which organisation has created a grading system for classifying cancer relationship with viruses?
The international agency for cancer research
What kind of virus is Hepatitis C?
A positive strand RNA virus.
What kind of a virus is a Papilloma virus?
A double stranded DNA virus
What kind of cancer cause Hepatitis C cause?
Liver Cancer
What kind of cancer does MErkel Cell polyoma virus cause?
Aggressive skin cancer
What is a behaviour that increases your chances of getting cervical cancer?
Smoking
What is a Risk factor in getting nasopharyngeal EBV associated cancer?
Eating salted fish because the preservatives contain a lot of nitrous amines which a mutagens
What are all babies in Taiwan vaccinated for since 1984?
Hepatitis B
Why do most viruses not cause cancer?
this could be because of the long standing co evolution between the virus and the host
What two viruses can remain in an episome and replicate separately to the host DNA?
EBV, KSHV
Describe the capsid of the Papilloma viruses?
this is an icosahedral shaped capsid and the main capsid protein is called L1
