Viruses Flashcards

1
Q

Poliovirus

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • polio
  • Salk and Sabin vaccine
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2
Q

Echovirus

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • aseptic meningitis
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3
Q

Rhinovirus

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • common cold
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4
Q

Coxsackie A virus

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • herpangina
  • hand-foot-mouth disease
  • acute lymphonodular pharyngitis
  • aseptic meningitis
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5
Q

Coxsackie B virus

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • pleurodynia
  • myocarditis
  • pericarditis
  • aseptic meningitis
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6
Q

HAV

A
  • Picornavirus (single, linear RNA)
  • nonenveloped
  • hepatitis A
  • vaccine
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7
Q

Norwalk virus

A
  • Calicivirus (single, linear RNA)
  • nonenveloped
  • gastroenteritis (adults)
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8
Q

HEV

A
  • Hepevirus (single, linear RNA)
  • nonenveloped
  • hepatitis E
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9
Q

Rotavirus

A
  • Reovirus (double, linear RNA)
  • nonenveloped
  • gastroenteritis (infants)
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10
Q

Coltivirus

A
  • Reovirus (double, linear RNA)
  • nonenveloped
  • arbovirus: the only transmitted by ticks
  • Colorado tick fever
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11
Q

HDV

A
  • Deltavirus (single, circular RNA)
  • enveloped
  • hepatitis D (alfa-interferon)
  • vaccine
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12
Q

Japanese virus

A
  • Flavivirus (single, linear RNA)
  • enveloped
  • encephalitis
  • vaccine
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13
Q

Yellow fever virus

A
  • Flavivirus (single, linear RNA)
  • enveloped
  • arbovirus
  • yellow fever
  • vaccine
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14
Q

West Nile virus

A
  • Flavivirus (single, linear RNA)
  • enveloped
  • arbovirus
  • encephalitis
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15
Q

Dengue virus

A
  • Flavivirus (single, linear RNA)
  • enveloped
  • arbovirus
  • dengue fever
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16
Q

HCV

A
  • Flavivirus (single, linear RNA)
  • enveloped
  • hepatitis C (alfa-interferon, ribavirin)
  • ass. with hepatocellular carcinoma
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17
Q

Rubella virus

A
  • Togavirus (single, linear RNA)
  • enveloped
  • rubella (German, “3-day” measles, trunkal rash, teratogen)
  • vaccine
18
Q

Eastern/Western virus

A
  • Togavirus (single, linear RNA)
  • enveloped
  • arbovirus
  • encephalitis
19
Q

Influenza viruses

A
  • Orthomyxovirus (single, linear RNA)
  • enveloped
  • influenza
  • ass. with Reye’s Syndrome
  • vaccine
  • amantidine, rimantidine, zanamivir, oseltamivir
20
Q

HTLV

A
  • Retrovirus (single, linear RNA)
  • enveloped
  • diploid
  • adult T-cell leukemia / lymphoma
  • chronic progressive myelopathy
21
Q

HIV

A
  • Retrovirus (single, linear RNA)
  • enveloped
  • diploid
  • infects CD4 Th cells
  • diagnosis confirmed by Western Blot
  • AIDS
  • zidovudine (AZT), lamivudine, stavudine, indinavir, ritonavir
22
Q

Measles virus

A
  • Paramyxovirus (single, linear RNA)
  • enveloped
  • measles (rubeola): Koplik’s spots
  • vaccine
23
Q

Mumps virus

A
  • Paramyxovirus (single, linear RNA)
  • enveloped
  • mumps (parotitis, orchitis, deafness)
  • vaccine
24
Q

RSV

A
  • Paramyxovirus (single, linear RNA)
  • enveloped
  • infants only
  • bronchiolitis
  • pneumonia
  • ribavirin
25
Q

Parainfluenza viruses

A
  • Paramyxovirus (single, linear RNA)
  • enveloped
  • croup
  • bronchiolitis
  • common cold
26
Q

Rabies virus

A
  • Rhabdobirus (single, linear RNA)
  • enveloped
  • rabies
  • vaccine
27
Q

Ebola virus

A
  • Filovirus (single, linear RNA)
  • enveloped
  • ebola, hemorrhagic fever
28
Q

Coronavirus

A
  • Coronavirus (linear, single RNA)
  • enveloped
  • common cold
  • SARS
29
Q

Hantavirus

A

= Sin Nombre virus

  • Bunyavirus (single, circular RNA)
  • enveloped
  • hantavirus hemorrhagic fever
30
Q

B19 virus

A
  • Parvovirus (single, linear DNA)
  • nonenveloped
  • smallest DNA virus
  • aplastic anemia
  • ass. sickle cell disease
  • erythema infectiosum (5th disease)
  • fetal infections
31
Q

HPV

A
  • Papillomavirus (double, circular DNA)
  • nonenveloped
  • papillomas (warts)
  • condylomata acuminatum (genital warts)
  • verruca vulgaris
  • cervical cancer
  • podophyllin, alfa-interferon, cidofovir
  • vaccine
32
Q

JC virus

A
  • Polyomavirus (double, circular DNA)
  • nonenveloped
  • progressive multifocal leukoencephalopathy
  • ass. with HIV
33
Q

Adenovirus

A
  • Adenovirus (double, linear DNA)
  • nonenveloped
  • pharyngitis
  • conjunctivitis
  • pneumonia
  • common cold
  • vaccine
34
Q

HBV

A
  • Hepadnavirus (double, circular DNA)
  • enveloped
  • reverse transcriptase
  • hepatitis B
  • ass. with hepatocellular carcinoma
  • alfa-interferon, lamivudine
  • vaccine
35
Q

Variola virus

A
  • Poxvirus (double, linear)
  • enveloped
  • largest DNA virus
  • smallpox (eradicated)
  • vaccine
36
Q

MCV

A
  • Poxvirus (double, linear DNA)
  • enveloped
  • largest DNA virus
  • molluscum contaginosum
37
Q

HSV-1

A
  • Herpesvirus (double, linear DNA)
  • enveloped (host nuclear membrane)
  • Tzank test
  • herpes labialis
  • keratoconjunctivitis
  • gingivostomatitis
  • reccurrent encephalitis
  • acyclovir, penciclovir, valacyclovir, famciclovir
38
Q

HSV-2

A
  • Herpesvirus (double, linear DNA)
  • enveloped (host nuclear membrane)
  • Tzank test
  • herpes genitalis
  • neonatal encephalitis
  • aseptic meningitis
  • acyclovir, penciclovir, valacyclovir, famciclovir
39
Q

VZV

A
  • Herpesvirus (double, linear DNA)
  • enveloped (host nuclear membrane)
  • Tzank test
  • varicella
  • ass. with Reye’s syndrome
  • zoster = shingles
  • acyclovir, famciclovir, valacyclovir
  • vaccine
40
Q

CMV

A
  • Herpesvirus (double, linear DNA)
  • enveloped (host nuclear membrane)
  • congenital abnormalities (primary viral cause of mental retardation)
  • cytomegalic inclusion disease
  • ganciclovir, valganciclovir, foscarnet
41
Q

EBV

A
  • Herpesvirus (double, linear DNA)
  • enveloped (host nuclear membrane)
  • infectious mononucleosis (necrotizing pharyngitis, heterophile test for screening)
  • ass. with Burkitt’s lymphoma
  • ass. with nasopharyngeal carcinoma
  • ass. with B-cell lymphoma
  • ass. with hairy leukoplakia
  • self-limiting 2-3 weeks
42
Q

HHV-8

A
  • Herpesvirus (double, linear DNA)
  • enveloped (host nuclear membrane)
  • Kaposi’s sarcoma