Viruses Flashcards
Adenovirus
Non enveloped.
Double strand
DNA
Droplet, direct contact, faecal oral.
Upper respiratory tract infection if inhaled.
Gastroenteritis if ingested.
Influenza A
Enveloped
Single strand
RNA
Droplet spread
Haemagglutin allows binding to CSM and entract into cell.
Neuraminidase cleaves glycoproteins to allow viral release from cell following replicaiton.
URTI
HIV
Enveloped Single strand RNA Bodily fluids and blood Infect CD4+ using reverse transcriptase to form DNA and host cell mechanisms to form new viral proteins and cells. Causes CD4 lysis.
AIDS if CD4
Hepatitis A
Enveloped
RNA
Faecal oral
Liver inflammation, hepatic jaundice.
Hepatitis B
Enveloped DNA double strand Bodily fluids and blood REplicates within hepatocyes Inflmmation --> host damage by immune mechanisms. Hepatomegaly, jaundice
Hepatitis C
Enveloped
RNA single strand
Blood to blood contact
Varicella zoster
Enveloped
Double strand DNA
Inhalation of virons, direct contact with blisters
Adaptive immune response, lifelong IgG for immunity.
Reactivated in immunocompromise -> shingle.
Norovirus
Envelope
DNA RNA
Non- enveloped RNA Single stranded Direct person to person Indirect from water or food Gastroenterirtis VOmiting, nausea, diarrhoea