Pneumonia Flashcards
Typical CAP Organisms stain and treatment
Streptococcus pneumonia gram positive cocci in chains
Haemophilus influenza - gram negative bacilli
Morazella catarrhalis
Atypical CAP organisms, definition, treatment?
Lack cell was so do not respond to beta lactams
Mycoplasma pneumonia - erythromycin (macrolide, inhibit protein synthesis)/clari (macrolide, inhibit protein synthesis) + dox (tetracycline - inhibits protein synthesis)
Staphylococcus aureus - amoxicillin + dox/clari + fluclox (penicillinase resistant penicillin - prevents peptidoglycan cell wall cross linking)
Legionella
Clamydia
IE COPD? organism?
H infuenza
Flu -> dry cough
Mycoplasma pneumonia
Following influenza
Staph aureus
Air conditioning acquired?
LEgionella
Features of legionella pneumonia? Treatment
lymphopoenia, hyponatraemia
Fluoroquinolone (quinolone - inhibits DNA gyrase - inhibits DNA synthesis) + clarithromycin (macrolide, inhibit protein synthesis)
HAP organisms?
Staphylococcus aureus - gram positive cocci in clusters
E.coli - gram neg rods
Psuedomonas aeruginosa
Ventilator associated pneumonia? Prevention? Treatment
Pseudomonas aeurginosa, staph aureus prevent by mouthwash, silver coated tube, wean off ASAP Ciprofloxacin PO (quinolone - inhibits DNA gyrase - inhibits DNA synthesis) Gentamicin IV (aminoglycoside - inhibits bacterial protein synthesis)
Pneumonia in alcoholics?
Klebsiella pneumoniae
Pneumonia in immunocompromised? treatment?
Pneumocytis jirovecii - dry cough, absence of chest signs
Co-trimoxazole
CURB1 treatment?
Amoxicillin (penicillin - inhibits bacterial peptidoglycan cell wall cross linking) PO 5 days
Doxycylcline (tetracycline - inhibits bacterial protein sytheiss) if pen allergic
CURB 2 treatment
Amox (penicillin - inhibits bacterial peptidoglycan cell wall cross linking) + dox/clari PO 7 days
CURB3 treatment?
Co-amoxiclav (penicillin - inhibits bacterial peptidoglycan cell wall cross linking + clavulanic acid - beta-lactamase inhibitor) + dox (tetracycline - inhibits bacterial protein sytheiss)/clari (macrolide, inhibit protein synthesis) IV 7 days
MRSA treatment?
Co-amoxiclav (penicillin - inhibits bacterial peptidoglycan cell wall cross linking + clavulanic acid - beta-lactamase inhibitor) + dox (tetracycline - inhibits bacterial protein sytheiss) /clari (macrolide, inhibit protein synthesis) + flucloxacillin (penicillinase resistant penicillin - prevents peptidoglycan cell wall cross linking)/vancomycin (glycopeptide - inhibits cell wall synthesis) if MRSA