Viruses Flashcards
1
Q
overview
A
-all forms of life have viruses
-they have co evolved with their hosts
-altered our history-AIDS, smallpox, flu
-many concepts and tools of molecular tools came from studying viruses
>4000 discovered
2
Q
filterable agents
A
- when filtered bacteria on 220 nm, filter became infectious
- when filtered viruses on 220 nm, filtrate was infectious
- viruses need to be seen using electron microscopes
- obligate intracellular–couldn’t culture on plates
3
Q
definition of a virus
A
- capsid encoding organism
- associated with all life forms
- obligate intracellular parasites
4
Q
capsid
A
protein shell that encapsulates the nucleic acid genome
5
Q
virion
A
particle encoded by virus genome-capsid and genome and other parts
6
Q
modular genomes
A
- contain capsid protein genes-stuctural proteins
- replicon-emzymes to copy the genome
- host cell interacting factors-non-structural proteins
7
Q
capsid stuctures
A
- helical symmetry
- icosahedral symmetry
8
Q
virion structure
A
- genome
- capsid
- maybe envelope
- capsid shape and genome type independent
9
Q
virus classification
A
- host cell (kingdom)-eukaryotic, prokaryotic, plant, animal, insect
- genome type-RNA/DNA, single or double stranded
- virion structure-enveloped or naked, helical, icosahedral, complex
10
Q
virion components
A
- genome segment
- nucleocapsid
- capsid of core
- tegument
- matrix
- envelope
- glycoprotein
- spike or fiber
- see slides for examples
