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PM3A > Viruses > Flashcards

Viruses Flashcards

1
Q

Define the baltimore classification

A

its the amount of steps needed for a certain virus to produce RNA

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2
Q

What are the 4 main types

A

0 step
1 step
2 step
3 step

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3
Q

what are 0 step Viruses

A

DsDNA
DsRNA
ssRNA -

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4
Q

What are 1 step Viruses

A

ssDNA
ssRNA +

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5
Q

What are 2 step Viruses

A

ssRNA RT

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6
Q

What is the 3 step virus

A

DsRNA RT

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7
Q

Give an example of DsDNA

A

HSV 1

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8
Q

Give an example of a ssDNA

A

Parovirus

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9
Q

Give an example of DsRNA

A

Rotavirus

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10
Q

Give an example of ssRNA +

A

Sars Cov 2

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11
Q

Give an example of ssRNA

A

Rabies

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12
Q

Give an example of ssRNA RT

A

HIV

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13
Q

Give an example of DsRNA RT

A

HBV

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14
Q

What does HIV stand for

A

Human immunodeficiency Virus

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15
Q

What does HIV target

A

targets CD4+T helper cells

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16
Q

What effect does it have

A

kills and destroys CD4+T helper cells leading to increased susceptibility towards new infections

17
Q

Define a HIV / Virus cell cycle

A

HIV binds to CD4 Receptor + CCR5 co receptor
Virus fuses with the membrane
uncoats and viral RNA enters the Host cell
DNA transcribed
enters nucleus integrating into the host genome
new viral RNA transcribed
new viral proteins produced
assembles at the membrane
budding leads to generation of mature viral particle released from cell

18
Q

How is HIV transmitted

A

Blood
Mucous

19
Q

What routes can HIV take

A

Sex
Mother
NEedle sharing
Blood transfusion

20
Q

What is Anti retroviral therapy (ART)

A

Treatment for HIV

21
Q

What is the combination of drugs used for art

A

2x nucleoside or tide inhibitor
1x integrase inhibitor / boosted protease inhibitor

22
Q

What is the combination of drugs used for art in pregnancy

A

2x nucleoside / tide

23
Q

Give an example of a NNRTI

A

Tenofovir fumarate
emtricitibane

24
Q

Give an example of a boosted protease inhibitor

A

Darunavir

25
Q

Give an example of integrase inhibitor

A

Raltegravir

26
Q

Define prep

A

pre exposure prophylaxis
- Truvada

27
Q

Define PEP

A

Post exposure prohpylaxis
Trevuda
Raltegravir
(4 weeks)

PM3A (4 decks)

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