Viruses Flashcards

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1
Q

define the structure of a virus

A

genetic material, protein coat, and sometimes an envelope containing lipids

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2
Q

the protein coat is also known as

A

capsid

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3
Q

explain a benefit of a virus having an envelope

A

it is easier to kill, since it is sensitive to heat, detergents and desiccation.

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4
Q

why are viruses considered obligate intracellular parasites?

A

they cannot reproduce independently

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5
Q

why do viruses need a host cell?

A

to express and replicate genetic information because they lack ribosomes to carry out protein synthesis

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6
Q

a virus replicates and creates:

A

virions, progeny that are released to infect more cells

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7
Q

bacteriophages target:

A

bacteria

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8
Q

what is the function of a tail sheath?

A

inject genetic material into a bacterium

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9
Q

what is the function of tail fibers?

A

help recognize and connect to the correct host cell

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10
Q

positive sense implies that the genome may be:

a. directly
b. indirectly

translated to functional proteins by the ribosomes of the host cell

A

a

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11
Q

negative sense implies that the genome requires synthesis of an RNA strand complementary to the negative-sense RNA strand. negative sense RNA viruses must carry a _________ in the virion to ensure that the complementary strand is synthesized

A

RNA replicase

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12
Q

In retroviruses, how many RNA molecules are found in the virion?

A

2

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13
Q

Retroviruses carry an enzyme known as ____________ which synthesizes DNA from single stranded RNA. The DNA then integrates into the host cell genome, where it is replicated and transcribed as if it were the cell’s own DNA

A

reverse transcriptase

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14
Q

true/false: viruses infect cells by attaching to specific receptors, and then either fusing with the plasma membrane, being brought in by endocytosis, or injecting their genome into the cell

A

true

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15
Q

viral progeny are released through: _____, ______, and ________

A

cell death, lysis and extrusion

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16
Q

lytic cycle vs. lysogenic cycle

A

lytic: bacteriophage produces massive amounts of virions until the cell lyses
lysogenic: the virus integrates into the host genome as a provirus or prophage, which reproduces along with the cell. the provirus leaves the cell in response to some stimulus and enters lytic cycle

17
Q

what are prions?

A

infectious proteins that trigger misfolding of other proteins, usually converting alpha helical structures into beta pleated sheets. this decreases the solubility and degradability of the protein

18
Q

what are viroids?

A

plant pathogens that can turn off genes, resulting in metabolic and structural derangements and even cell death