Viruses Flashcards

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1
Q

What test catches dysplasia and carcinoma by cytology?

A

Pap Smear Test

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2
Q

reservoir for Hantavirus

A

Rodent feces and urine

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3
Q

Another name fore Measles

A

Rubeola

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4
Q

Signs of chronic Hepatitis

A

1) Cirrhosis

2) Hepatocellular Carcinoma

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5
Q

Ground Glass Inclusions… You should think

A

Polyoma Virus

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6
Q

Signs of Polio

A

1) Loss of reflexes
2) Muscle aches
3) Paresthesia

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7
Q

Diseases caused by CMV

A

1) CMV Mononucleosis - More pronounced fever
2) Chorioretinitis - Immunocompromised
3) TORCH
- Most common cause of intellectual disability

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8
Q

Symptoms of HSV I and II

A

1) HSV I : Oral Herpes “Cold Sore”

2) HSV II: Genital Herpes

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9
Q

What is Herpangina

What is it caused by?

A

Bilateral and Posterior vesicular eruption in back of throat

Coxsackie A

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10
Q

All viral hepatitis show ___ in labs

A

1) Increased:
- Liver Function Test: AST and ALT
- Bilirubin

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11
Q

What virus induces Giant Cell Formation

A

RSV

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12
Q

What does IgM anti-HBcAg mean

A

New Hep B infection

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13
Q

Cytomegalovirus (CMV) Cytopathic effect

A

Owl’s Eve inclusion

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14
Q

What causes Rabies

A

Rhabdoviridae

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15
Q

What causes Equine Encephalitis

A

Togaviridae

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16
Q

Cytological feature in Parvo

A

Giant Erythroblasts

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17
Q

MOA of JC Polyomavirus

A

Demyelinating Disease of CNS

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18
Q

If a pregnant women acquires parvo what occurs

A

1) Parvo induced anemia –> Hydrops and Death

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19
Q

High Risk strains of HPV

A

16, 18, 31, 45

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20
Q

What virus causes common and genital warts

A

HPV

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21
Q

Population for HHV-8

A

1) endemic in eastern europe/middle eastern males
2) African children
3) AIDS

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22
Q

When to start pap smear

A

21

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23
Q

Population of Molluscum contagiosum

A

1) Youn Children

2) HIV Pts

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24
Q

Diseases of Flaviviridae family

A

1) Yellow Fever
2) Dengue Fever
3) Zika Virus
4) West Nile Virus

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25
Q

Highly infectious childhood disease with rash that leads to crust/scabs on the face and trunk

A

Varicella (Chickenpox)

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26
Q

What virus causes high fever, muscle aches, cough, N/V in the southwestern USA and is transmitted by rodent feces/urine.

A

Hantavirus

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27
Q

Reservoir for Coronavirus

A

Bat

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28
Q

Disease caused by EBV

A

EBV Mononucleosis

  • Fever
  • Sore Throat
  • Lymphadenopathy
  • Hepatosplenomegaly
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29
Q

List the DNA Viruses

A

1) Herpesvirus
2) Hepadnavirus
3) Adenovirus
4) Papovavirus
5) Parvovirus
6) Poxvirus

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30
Q

List the Paramyxoviridae Viruses

A

1) Measles
2) Rubella
3) Mumps
4) Parainfluenza
5) RSV
6) Metapneumovirus

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31
Q

Diagnosis of EBV

A

1) Heterophile antibody test (monospot)

2) EBV antibody test (if monospot negative)

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32
Q

What virus attacks the anterior motor neurons

A

Polio virus

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33
Q

Which Hep Viruses are chornic

A

1) B, C, D, E: Genotype 3

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34
Q

COVID-19 symptoms

A

1) Decrease Taste and Smell

2) Fever and Cough

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35
Q

Population: EBV

A

1) Preadolescents and Adolescents

2) Young Adults

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36
Q

Shape of Rabies virus

A

Bullet Shaped

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37
Q

____ is responsible for common could and SARS

A

Coronavirus

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38
Q

What are Koplik’s Spots

A

1) White oral lesions with red periphery

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39
Q

Mild measles-like illness is caused by

A

Rubella

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40
Q

What is characteristic of Measles

A

1) Rash that starts on face and spreads downward

2) Koplik’s Spots

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41
Q

What is the moct common sexually transmitted disease

A

HPV

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42
Q

Consequence of Measles

A

Subacute Sclerosing Panencephalitis

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43
Q

Disease Manifestations in Parvovirus

A

1) Erythema Infectiosum (Fifth’s Disease)

2) Transient Aplastic Crisis

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44
Q

What causes Kaposi Sarcoma

A

HHV-8

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45
Q

What is Subacute Sclerosing Panencephalitis and what bacteria causes it?

A

1) Slowly progressive neurologic disease
- Months and years after
- Forgetfulness, Distractibility, and Hallucinations

46
Q

Virulence Factors of Influenza

A

1) Hemagglutinin: Binds to sialic acid receptors - Upper respiratory tract, RBC
2) Neuraminidase: Disrupts mucin barrier

47
Q

Symptoms of West Nile

A

1) Fever
2) Headache
3) Meningitis
4) Encephalitis

48
Q

Complications of Covid-19

A

1) Thromboembolic Complications

2) Respiratory Failure (ARDS) –> Respiratory and multiorgan failure/ death

49
Q

Symptoms of Herpes Zoster 9shingles)

A

1) Painful Lesion in Dermatomal Distribution

50
Q

What is the characteristic feature of parvo virus

A

Rash slapped cheeks

51
Q

General Population for Polyoma virus

A

Immunocompromised

52
Q

Flaviviridae Transmission

A

Febrile Mosquito-born illness

53
Q

Location of Hanta Virus

A

Southwest USA

54
Q

What do the High risk strains of HPV cause?

A

Cervical Cancer

55
Q

Transient Aplastic Crisis Signs

A

1) Temporary Anemia

- Severe if concomitant hemolytic disease (sickle cell, thalassemia)

56
Q

Consequences of Polio

A

1) Single Limb paralysis
2) Paraplegia
3) Quadriplegia

57
Q

Diseases caused by Coxsackie A

A

1) Herpangina

2) Hand, Foot, and Mouth Disease

58
Q

JC Polyomavirus Diseases

A

1) Progressive Multifocal Leukoencephalopathy

- Behavioral, speech, cognitive, and motor impairment

59
Q

Viruses that cause Diarrhea

A

1) Norovirus (Norwalk Virus): Cruise ships

2) Rotovirus: Significant cause of infant mortality worldwide

60
Q

____ is caused by congenital rubella

A

Cataracts

61
Q

Signs of Fulminant Viral Hep.

A

1) Rapid Severe Hepatitis

2) Underlying Liver Disease is @ risk

62
Q

Location of Polio

A

1) Pakistan
2) Afghanistan
3) Nigeria

63
Q

Sx of Hantavirus

A

1) High Fever
2) Muscle Aches
3) Cough
4) N/V

64
Q

cause of pneumonia in young children esp. infants

A

RSV

65
Q

2 cause of pneumonia in young children, bronchiolitis

A

Metapneumovirus

66
Q

Signs of Rabies

A

1) Hydrophobia: Pharyngeal spasms on swallowing
2) Agitation/aggressive/hallucinatory behavior
3) Paralysis, coma and death

67
Q

Signs of Erythema Infectiosum (Fifths Disease)

What Virus Causes it

A

1) Rash slapped cheeks
2) Low Grade Fever - (1st symptom)

Parvo

68
Q

What does HBsAg indicate?

A

Present Live Virus (Infection)

69
Q

Diseases caused by Polio Virus

A

1) Aseptic Meningitis - has repeat fever

2) Flaccid Asymmetric Paralysis

70
Q

EBV: Cancers

A

B cell lymphoma (Hodgkin and Burkitt)

Nasopharyngeal Carcinoma

71
Q

Types of Polyoma virus

A

1) BK

2) JC

72
Q

Location of Flaviviridae viruses

A

Warm/tropical areas

73
Q

Pt comes in with parotitis and swollen testes. What is sus.

A

MUMPS

74
Q

___ can cause an increase clotting times due to loss of liver derived coagulation factors

A

Viral Hepatitis

75
Q

What virus causes encephalitis and is Transmitted by a mosquito

A

Togaviridae

76
Q

Population of JC polyomavirus

A

AIDS

77
Q

Key features of Zika

A

1) Fever
2) Rash
3) Joint Pain
4) Microcephaly in infant *****88

78
Q

___ causes Croup w/ infection of larynx and/or bronchus: Barking cough

A

Parainfluenza

79
Q

Transmission of EBV

A

1) Contaminated Toothbrush or Utensils

- saliva

80
Q

Key features of Yellow Fever

A

Hepatitis w/ Jaundice

81
Q

What mammals can become infected with Togaviridae

A

Horses and Humans

82
Q

What does IgG Anti-HBcAg mean?

A

Older or previous Hep B infection

83
Q

What does HBsAb indicate?

A

1) Resolved Infection

2) Immune

84
Q

Diseases caused by HSV

A

1) Oral and Genital Herpes
2) Herpetic Whitlow
3) Neonatal Infection (TORCH)
4) Encephalitis # 1 cause of viral encephalitis

85
Q

Presentation of Influenza

A

1) High Fever
2) Rhinorrhea
3) Cough
4) Myalgias
5) Arthralgia

86
Q

Disease caused by adenovirus (DNA virus)

A

1) Upper Respiratory Tract Illness

2) Pharyngitis and/or cold-like symptoms

87
Q

MOA of Rabies

A

Virus migrates up the nerve axon to the CNS

88
Q

Symptoms of Kaposi Sarcoma

A

Red-purple nodules or plaques

89
Q

Cause of Hand, Foot and Mouth Disease

A

1) Mild Fever

2) Erythematous/Vesicular lesions on hands, feet, in/around mouth

90
Q

____ = intermediate grade vascular tumor

A

Kaposi Sarcoma

91
Q

MOA of EBV

A

Infects B cells via C3d receptors

92
Q

Clinical Manifestations of Mumps

A

1) Fever
2) Facial Swelling and Pain: Parotitis
3) Erythematous Swollen Testes ( Orchitis)

93
Q

Signs of Acute Viral Hep

A

1) Jaundice:

- Yellowing of Eyes and Skin

94
Q

What causes Fulminant Hepatitis

A

Coinfection w/ B and D

95
Q

What family does Molluscum Contagiosum and Small Pox Belong to>

A

Poxviridae

1) Molluscum Contagiosum “water warts”
2) Smallpox

96
Q

Key Features of Dengue Fever

A

Breakbone fever - Severe backache and joint pain

97
Q

Presentation of Molluscum Contagiosum

A

1) Water Warts

- Superficial Skin Infection: DOME shape flesh colored lesion w/ central dimple

98
Q

Types of Togaviridae

A

1) Western Equine Encephalitis

2) Eastern Equine Encephalitis

99
Q

Top two causes of common cold

A

1) Rhinovirus

2) Coronavirus

100
Q

Key issue of Rubella

A

TORCH: Congenital defects of heart, eye, and CNS

101
Q

Neoplasia risks in HIV

A

1) Lymphomas: B cell lymphomas (EBV)
2) Kaposi sarcoma - HHV-8
3) Cervical Carcinoma - HPV

102
Q

Diseases caused by BK Polyomavirus

A

1) Bladder - Hemorrhagic Cystitis
2) Kidney - Nephritis
- Ground glass inclusion

103
Q

Transmission of Rabies

A

1) Bite (saliva) by warm blooded animal
- Bat
- Raccoon
- Skunk
- Fox

104
Q

Which Hepatitis Strains are Parenteral and Enteric

A

1) Parenteral
- B
- C
- D

2) Enteric
- A
- E

105
Q

Human Herpes Virus 8 (HHV-8) transmission

A

Sexual/Saliva

106
Q

What is HHV-6

A

Roseola - self limited illness of young children

- High fever that resolves followed by immediate rash

107
Q

BK Polyomavirus population

A

Renal Transplant Pts

108
Q

Which type of hep. predisposes you to hepatocellular carcinoma

A

1) B, C, D –> Chronic Hepatitis

109
Q

Which hep. strains cause acute viral hepatitis

A

1) A - more common

2) E

110
Q

Cold Symptoms

A

1) Sore Throat
2) Rhinorrhea
3) Cough
4) Malaise

111
Q

Where are diarrheal viruses present

A

Institutional settings: Daycare and nursing homes

112
Q

Which three opptornistic infections are seen in HIV pts

A

1) Oral Thrush - Candida
2) Cryptococcus Neoformans
3) Toxoplasmosis: Ring enhancing lesions