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Micro Exam 6 > Virus SSTI > Flashcards

Virus SSTI Flashcards

1
Q

Papillomas Nodules

A

Warts

Molluscum

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2
Q

Warts

A

HPV

Papovaviridae family

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3
Q

Molluscum Contagiosum

A

Molluscum Contagiosum Virus

Poxyviridae family

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4
Q

Ulcers and purulent lesions

A

Herpes labialis
Chicken pox
Herpes zoster/ shingles
Small pox

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5
Q

Cold sores

A

Herpes labialis
Herpes simplex virus
Herpesviridae family

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6
Q

Chicken pox

A

Varicella zoster virus

Herpesviridae family

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7
Q

Herpes Zoster

A

Shingles
VZV reactivation
Herpesviridae family

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8
Q

Small pox

A

Variola virus

Poxiviridae family

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9
Q

Childhood rash & fever

A

Measles
German measles
Fifth disease / Erythema
Roseola infantum

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10
Q

Rubeola

A

Measles
Measles Virus
Paramyxovirus familly

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11
Q

German Measels

A

Rubella Virus

Togaviridae

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12
Q

Erythema infectiosum

A

Fifth Disease
B19 Parvovirus
Parvoviridae

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13
Q

Roseola infantum

A

HHV 6 & 7

Herpesviridae

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14
Q

HPV

A

Non enveloped dsDNA
Replication tied to tissue infected
Expansion of epithelial layer

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15
Q

HPV VF

A

E7 inhibits RB
E6 inhibits p53
100 serotypes

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16
Q

HPV Transmission

A

Direct contact cut/abraisons
New HPV virions form in
suprabasal layer of skin

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17
Q

HPV symptoms

A

Warts exophytic
Plantar warts
Punctate hemorrhage
Flat warts mouth

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18
Q

HPV Diagnose and treat

A 
Clinical signts: Hyperkeratosis & Koilodal cells.
Cryotherapy
Cytotoxic chemical
Surgical removal
HPV vaccine 16 & 18
not cutaneous
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19
Q

MCV

A

Large dsDNA

Replicates in cytoplasm

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20
Q

MCV Transmission

A

Direct contact w/ lesion
STD
On face or genitals

21
Q

MCV Symptoms

A

Painless pearly nodules
Central depression purulent fluid
Molluscum bodies

22
Q

MCV Diagnose & Treat

A

Signs
Resolves w/ out or
Surgery cryotherapy

23
Q

HSV

A

Enveloped dsDNA
Latent n Lytic
HSV 1 oral
HSV 2 genital

24
Q

HSV Transmission

A

Direct contact w/ lesion or saliva.
Follows PNS
TGG

25
Q

HSV Symptoms

A
  1. cold sore
  2. recurrent
    Simplex keratitis blindness
    Whitlow neonates toes
    Encephalitis
26
Q

HSV Treat

A

Acyclovir

27
Q

Varicella zoster virus

A

Enveloped dsDNA

28
Q

VZV transmision

A

Resp secretions
Saliva
Direct contact

29
Q

VZV Symptoms

A

Lesion mostly in trunk face and scalp
Vesicle - postules - scabs
Bacterial infection of lesions
Pnuemonia or dissemination

30
Q

VZV Diagnose & Treat

A 
Signs
Serology
Vaccine - LIVE ATTENUATED
Also helps against SHINGLES
Acyclovir
31
Q

VZV Shingles Symptoms

A

Paresthesia prodrome
vesicular lesions on trunk
unilateral fever malaise
Postherpetic neuralgia

32
Q

Variola virus

A

Large dsDNA
Replicates in cytoplasm
Own enzymes
Strictly human

33
Q

Variola Transmission

A

Aerosol
Contact lesion
Contagious until all scabs cleared

34
Q

Variola symptoms

A 
Abrupt high fever
Malaise headache
Myalgia nausea
Lesion on mouth & skin
Centrifugal and 
On palms and soles
Resp tract
Encephlitis
Hemorrhagic
Mortality higher
35
Q

Variola Diagnose & treat

A

Vaccine
LIVE ATTENUATED
Eradicated

36
Q

Measles Virus

A

Enveloped ssRNA
F gene fusion
HA attachement

37
Q

Measles Transmission

A

Resp. shed in nasopharynx
Highly contagious
Infect up to 2 hr in air

38
Q

Measles symptoms

A 
Cough
Coryza
Conjunctivitis
Kopliks spots
Annorhexia, diarrhea otitis media, pneumonia
encephalitis seizures and death
39
Q

Measles diagnose & treat

A

Immuno prophalaxis
Vaccine
LIVE ATTENUATED

40
Q

Rubella Virus

A

Enveloped

+ssRNA

41
Q

Rubella transmission

A

Resp

42
Q

Rubella signs

A

Maculopapular rash 1st face and the downward
Fainter and don’t coalesce
arthralgia arthritis
Newborns deafness blindness CHD

43
Q

Rubella diagnose and treat

A

direct culture rtPCR serology
VACCINE
LIVE ATTENUATED
to prevent congenital syndrome

44
Q

B19

A

ssDNA
Grows in mitotic active cells
Uses host

45
Q

B19 symptoms

A

Slap cheek
Fever
Rash lacelike
Aplastic chrisis: chronic anemia arthralgia arthritis hydrop fetalis

46
Q

HHV 6/7

A

Enveloped dsDNA

47
Q

HHV 6/7 workings

A

Prim infect by 3

Replicates in T and B cells

48
Q

HHV 6/7 signs

A

High fever 4 days
Maculopapular rash follows
7 - t cell infect later than 6

Micro Exam 6 (6 decks)

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