Bact SSTI II Flashcards
GAS VF
Capsule (hyaluronic)
Adhesion (F, M and LTA)
Toxins ( O, S and SA)
GAS SSTI diseases
Impetico
Erysipelas
Cellulitis
Necrotizing Fasciitis
GAS Glomerulonephritis
Type III hypersensitivity
M protein, Streptokinase
3-6 wks post cutaneous infection
Reduce CH50 & C3
GAS Treatments
Penicillan
Erythro/azithromycin
Oxacillin or Vancomycin if S aureus co infection
Pseudomonas aeruginosa
G-, O+, hemolytic Pyocanin Minimalis Nosocomial Oppurtunistic
Psuedomonas VF
Mucoid ps capsule alginate Adhesins lps Toxins Enzymes Antibiotic resistance
Pseudomonas diseases
Burn wounds
Folliculitis
Osteochondritis after penetrating injury
Ecthyma gangrrenosum
Ecthyma gangrenosum (pseudomonas)
After septicemia
purpuric macule - to hemorrhagic bulla that ruptures
Green Nails (pseudomonas)
Grows as biofilm after pre existing condition, makes it nice and moist
Webspace intertrigo (pseudomonas)
Macerated eroded skin interdigital toes
Excessive moisture
Tinea may be present
Pseudomanas treatment
Varies combo
aminoglycoside + b lactam
Prevent Keep dry
no unnecessary antibios
Clostridium
G +, ANAEROBIC,
spores tough, ubiquitous
C perfingien diseases
Gas gangrene myonecro Cellulitis Fasciitis Supporative myositis A-E important strains Other - food poison, necro entero & septic
C perfringens toxins
alpha - phospholipase,
Beta - loss of mucosa
A Enterotoxin -binding and heat labile SAg
gas gangrene
In traumatic wounds crepitations gas production cellulitis 1st, then destruction and spread toxin shock death TREAT IMMEDIATLE REMOVE DEAD & give CLINDAMICIN or metronidazole