virus (part of microbio) Flashcards
Listeria monocytogenes
Gram-positive rod
L. monocytogenes targets the young and old, pregnant women, and
immunocompromised individuals; about 15% of those infected die.
Viruses can exist
extracellularly or intracellularly
extracellular viruses
are inactive because they possess few, if any, enzymes and cannot reproduce outside of living cells.
intracellular viruses
exist primarily as replicating nucleic acids that induce the host to synthesize viral components from
which progeny virions are assembled and eventually released.
ICTV
International Committee for Taxonomy of Viruses
virion
complete virus particle
Virions size
10 to 400 nm in diameter
largest known virus
mimiviruses
Acidianus two-tailed virus ATV
dsDNA
9 structural proteins
tail protein is 800 aa long
produces tails in extracellular/inert state
nucleocapsid
composed of a nucleic acid,
either DNA or RNA, and a protein coat called the capsid
function of caspid
protects genome + aids in transfer
protomers
caspid proteins encoded by the viral genome
tobacco mosaic virus (TMV) capsid structure
constructed using single type of protomer
TMV protomer len
158 aa
TMV genome
6400 nucleotides
envelope
a lipid layer external to the nucleocapsid
types of caspid symmetry
helical, icosahedral, and complex
helical caspids
shaped like hollow tubes w protein walls. Ex TMV
TMV stucture
rigid tube, RNA lies btwn grooves in the spiral of encoded proteins
influenza virus enveloped?
true
examples of helical
TMV, influeza
Icosahedral
regular polyhedron with 20 equilateral tri
angular faces and 12 vertices
enclosing efficiency of types of caspids
icosahedral>
capsomers
ring- or knob-shaped units each usually made of pentamers or hexamers, make up the icosahedral caspids
complex symmetry example
poxviruses + large bacteriophages
icosahedral exmaple
adenovirus
poxivirus virions affect
animal