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Virus Flashcards

1
Q

All enveloped viruses acquire their envelope from plasma membrane except

A

Herpesviruses

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2
Q 
Naked viral genome infectivity
ssRNA (+)
ssRNA (-)
dsRNA
dsDNA
A

ssRNA (+)

dsDNA except poxviruses and HBV

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3
Q

Segmented genome

A

Orthomyxovirus

Reovirus

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4
Q

Decrease in acid production by infected, dying cells seen using

A

Phenol red

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5
Q

Only live-attenuated vaccine that may be given to HIV-positive patients

A

MMR

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6
Q

All DNA viruses have double-stranded DNA except

A

Parvovirus

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7
Q

All DNA viruses have linear DNA except

A

Papilloma
Polyoma
Hepadna

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8
Q

All DNA viruses are icosahedral except

A

Poxvirus

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9
Q

All DNA viruses replicate to the nucleus except

A

Poxvirus

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10
Q

Erythema infectiosum (fifth disease)

A

Parvovirus B19

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11
Q

Only virus with fiber

A

Adenovirus

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12
Q

Most common cause of viral conjunctivitis

A

Adenovirus

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13
Q

HPV strains causing genital warts

A

6 and 11

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14
Q

HPV strains causing carcinomas

A

16, 18, 31 and 33

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15
Q

Progressive multifocal leukoencephalopathy (PML)

A

JC polyoma virus

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16
Q

Hemorrhagic cystitis and nephropathy

A

BK polyoma virus

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17
Q

Visualization of HSV

A

Tzanck smear

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18
Q

Drug of choice for HSV

A

Aciclovir

No effect on latent state!

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19
Q

Ramsay Hunt syndrome

A

Herpes zoster oticus

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20
Q

Infectious mononucleosis

Positive heterophil test

A

EBV

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21
Q

Infectious mononucleosis

Negative heterophil test

A

CMV

Toxoplasma

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22
Q

Drug of choice for CMV retinitis

A

Foscarnet

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23
Q

Malignancies caused by Epstein-Barr virus

A

Burkitt’s lympomma

Nasopharyngeal carcinoma

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24
Q

Drug of choice for molluscum contangiosum

A

Cifodovir

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25
Q

Hepatitis B is associated with what autoimmune vasculitides

A

Polyarteritis nodosa

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26
Q

Drug of choice for hepatitis B

A

Interferon-alpha and lamivudin

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27
Q

All RNA viruses have single-stranded DNA except

A

Reovirus

Rotavirus

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28
Q

All DNA viruses replicate in the cytoplasm except

A

Influenza

Retrovirus

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29
Q

Most common clinical form of polio

A

Abortive poliomyelitis

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30
Q

Most common cause of myocarditis and pericarditis

A

Coxsackie virus

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31
Q

Echovirus

A

enteric cytopathic human orphan

32
Q

Herpangina is caused by

A

Coxsackie virus

33
Q

Most important test for hepatitis A

A

Anti-HAV IgM

34
Q

Most common cause of nonbacterial diarrhea in adults

A

Norvovirus

35
Q

Most common cause of childhood diarrhea

36
Q

Most common cause of respiratory tract infections

37
Q

Influenza: binds to cell surface receptor

A

Hemagglutinin

38
Q

Influenza: cleaves sialic acid

A

Neuraminidase

39
Q

Source of influenza B virus

A

Humans only

40
Q

Measles: multinucleated giant cells

A

Warthin-Finkedely bodies

41
Q

Damson disease

A

Subacute sclerosing panencephalitis

42
Q

Most improtant cause of pneumonia and brohchiolitis in infants

A

Respiratory syncytial virus

43
Q

Drug of choice for respiratory syncytial virus

44
Q

Rabies: touching or feeding animals, licks on skin

A

No treatment

45
Q

Rabies: nibbling of uncovered skin

46
Q

Rabies: minor scratches or abrasions without bleeding

47
Q

Rabies: licks on unbroken skin

48
Q

Rabies: transdermal bites or scratches

A

Vaccine + immunoglobulin

49
Q

Rabies: Contamination of mucous membranes with saliva from licks

A

Vaccine + immunoglobulin

50
Q

Coronavirus binds to

A

ACE-2 receptor

51
Q

Most virulent of dengue serotypes

52
Q

Most prevalent blood-borne antigen

A

Hepatitis C virus

53
Q

Main cause of essential mixed cryoglobulinemia

A

Hepatitis C

54
Q

HIV: transmembrane/fusion protein

55
Q

HIV: surface/attachment protein

56
Q

HIV: major capsid protein

57
Q

HIV: nucleoprotein

58
Q

HIV: outer matrix protein

59
Q

HIV: gene coding for reverse transcriptase, protease, integrase

60
Q

HIV: gene responsible fro decreasing CD4 and class I MHC proteins

61
Q

Most common AIDS-defining illness

62
Q

HIV: presumptive diagnosis

63
Q

HIV: definitive diagnosis

A

Western blot

64
Q

Perinatal prevention of HIV

A

Zidovudine

65
Q

True or false: all helical viruses are naked

66
Q

All viruses are haploid except

A

Retroviruses

67
Q

Segmented viruses

A

Orthomyxovirus

Reovirus

68
Q

Henderson-peterson bodies

A

Molluscum contagiosum

69
Q

Guarnieri bodies

A

Molluscum contagiosum

70
Q

Treatment for molluscum contagiosum

71
Q

Most common cause of aseptic meningitis

A

Coxsackie virus

72
Q

True or false: rhinoviruses are acid stable

A

Acid labile

73
Q

True or false: measles virus has hemagglutinin and neuraminidase

A

Hemagglutinin only

74
Q

True or false: RSV has hemagglutinin and neuraminidase

A

None. Fusion protein

75
Q

Treatment for RSV infection

76
Q

Viral arthritis

A

Parvovirus B19

77
Q

Vaccine frim reassorted bovine and human viruses

Microbiology (12 decks)

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