Virology: Influenza Flashcards
What is the 8 symptoms of flu
Abrupt onset
Body aches
Fever
Fatigue
Couch
Headache
Systemic effects
Seasonal
What is the 6 symptoms of cold
Gradual onset
Sneezing
Stuffy nose
Sore throat
Local effects
All year
What is zoonosis
Infection acquired from another species that is transmitted & cause disease
What zoonotic diseases cause infection in human
H1-3 & N1-2
What is the function of H protein
Haematglutinin to attach to cell membrane
What is the function of N protein
Neuraminidase
Release from cell membrane
What is the antigenic shift
Reassortment occur when a new gene is added into the sequence & reassortant if formed that is new to immunity
What does antigenic shift cause
Pandemic
What is the antigenic drift
RNA viruses do not proofread & small/minor changes are made that still cause an infection in Humana s it is new to the immune system
What does antigenic drift cause
Epidemic
How is influenza transmitted
Droplet, direct contact & fomites
What is the 6 population at risk for influenza
Immunocompromised
Morbidly obese
TB
Chronic disease
Over 65 years & under 2 years
Pregnant
What is the 2 types of influenza vaccines
Live attenuated
Inactive form
What 3 populations should receive the influenza vaccine
Over 6 months old w/ risk factors
HCP
Pregnant
What 3 populations should not receive the influenza vaccine
Hypersensitive to eggs
Under 6 months
Acute febrile disease
