Virology Flashcards
Which virus doesn’t replicate at body temperature well? Note: so when latent but can’t shed
Canine herpes which also results in neonatal death- herpes parties for bitches
Which herpes lead to secondary bacterial infection?
Bovine Rhinotrachitis and Feline Rhinotrachitis
Procine herpes [aujeszky disease] is unique because
It is the only alpha herpes that goes across species but is not zoonotic
In equine herpes mylencephalitis which tissue is infected by virus
The brain and spinal cord, endothelium
No clinical signs in reservoir host and transmission is NOT between susceptible hosts; it has to go through the reservoir
[Hint: infects lymphocytes]
Gammaherpes - Carharral Malignant Fever
Which virus is only reproductive and results in mummification before the 70day gestation mark?
Porcine parvovirus SMEDI
Which transplacental infection results in abortion and cerebellar hypoplasia?
Feline panleukopenia - feline parvovirus
Which dsDNA virus is non-enveloped
herpes, parvo, poxvirus
Parvovirus - can survive in the environment/ feces
Which type of pox is zoonotic and epidermal?
Leporipox on rabbits and squirrels
Leporipox is different because it affects ___ cells
mesenchymal cells and not epithelial cells
With poxvirus what gives life long immunity vs transient immunity
Systemic infection gives life long immunity
Local infection gives transient immunity
Which strand + or- can go directly to ribosome?
The positive sense strand goes to the ribosome directly to be transcribes but the Negative sense RNA has to make a complementary positive sense strand first
Which virus is associated with old dog encephalitis? [Note: will see keratinized nose and paw]
Canine distemper
Old dog encephalitis happens years after recover and leads to neurological deterioration and death
Highly immunogenic with vaccine
Which bovine diseases are associated with paramyxovirus and the bovine respiratory disease complex?
Bovine parainfluenza 3 and bovine respiratory synactia virus
What is the rabies flow from peripheral nerves to the brain called?
Retrograde axoplasmic flow
Feline panleukopenia/ parvovirus is…
Canine distemper is….
Rabies is…
Vesicular Stomatitis is…
Endemic
Subclinical infection exists in this rhabdovirus and this paramyxovirus
Vesicular Stomatitis
Canine distemper
BRSV vs BI3 which is immunosuppressive
BRSV
Hemagglutinin
Antigen on othromyxovirus for attachment and fusion
Neuraminidase
Antigen on orthomyxovirus for cleaving viral receptors and increase entry of vision and increased transmission
In terms of H/N reassortment, what are pigs?
Reassortment host
What is unique about the CPE in orthomyxoviruses
no inclusion bodies
Genetic reservoir for influenza? Generation of new subtypes come from this animal
Aquatic birds
3 SYSTEMS AFFECTED BY CORONA
GI, respiratory, CNS
Feline corona virus explained with 2 virus names, mutation in ___ and ____ leading to immune mediated ____
Feline Enteric coronavirus into feline infectious peritonitis
Because of spike protein change in monocytes and macrophages
Leading to immune mediated vacuities if not cured
TGE vs Porcine Epidemic Diarrhea virus
Both cause diarrhea and baby pig mortality
TGE is a coronavirus
This blunts the intestinal villi of bovines causing diarrhea and less absorption
Betacoronavirus Bovine coronavirus
The bovine viral diarrhea virus with non cytopathic strain before 150 days results in…
Shedding and persistent infection
Shedding and persistent infection of BVDV can lead to mucosal disease how
with new cytopathic strain added or with a mutation
BVDV is from what family
Pestivirus ssRNA vertical or horizontal transmission
What changes when the Prpc becomes the Prpsc
It goes from a alpha helical structure to a beta stealth which is strong and resistant to protease so it accumulates in the neurons
Why is a prion not immunogenic?
because its a protein not a virus
Deer is to Chronic wasting disease as bovine is to
Bovine Spongiform encephalopathy (humans can get this too)
Oncogenes retrovirus name 2 and how they differ
Feline Leukemia (FeLV) and Bovine Leukosis (BLV)
