Virology Flashcards

1
Q

Which virus doesn’t replicate at body temperature well? Note: so when latent but can’t shed

A

Canine herpes which also results in neonatal death- herpes parties for bitches

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2
Q

Which herpes lead to secondary bacterial infection?

A

Bovine Rhinotrachitis and Feline Rhinotrachitis

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3
Q

Procine herpes [aujeszky disease] is unique because

A

It is the only alpha herpes that goes across species but is not zoonotic

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4
Q

In equine herpes mylencephalitis which tissue is infected by virus

A

The brain and spinal cord, endothelium

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5
Q

No clinical signs in reservoir host and transmission is NOT between susceptible hosts; it has to go through the reservoir
[Hint: infects lymphocytes]

A

Gammaherpes - Carharral Malignant Fever

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6
Q

Which virus is only reproductive and results in mummification before the 70day gestation mark?

A

Porcine parvovirus SMEDI

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7
Q

Which transplacental infection results in abortion and cerebellar hypoplasia?

A

Feline panleukopenia - feline parvovirus

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8
Q

Which dsDNA virus is non-enveloped
herpes, parvo, poxvirus

A

Parvovirus - can survive in the environment/ feces

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9
Q

Which type of pox is zoonotic and epidermal?

A

Leporipox on rabbits and squirrels

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10
Q

Leporipox is different because it affects ___ cells

A

mesenchymal cells and not epithelial cells

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11
Q

With poxvirus what gives life long immunity vs transient immunity

A

Systemic infection gives life long immunity
Local infection gives transient immunity

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12
Q

Which strand + or- can go directly to ribosome?

A

The positive sense strand goes to the ribosome directly to be transcribes but the Negative sense RNA has to make a complementary positive sense strand first

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13
Q

Which virus is associated with old dog encephalitis? [Note: will see keratinized nose and paw]

A

Canine distemper
Old dog encephalitis happens years after recover and leads to neurological deterioration and death
Highly immunogenic with vaccine

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14
Q

Which bovine diseases are associated with paramyxovirus and the bovine respiratory disease complex?

A

Bovine parainfluenza 3 and bovine respiratory synactia virus

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15
Q

What is the rabies flow from peripheral nerves to the brain called?

A

Retrograde axoplasmic flow

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16
Q

Feline panleukopenia/ parvovirus is…
Canine distemper is….
Rabies is…
Vesicular Stomatitis is…

A

Endemic

17
Q

Subclinical infection exists in this rhabdovirus and this paramyxovirus

A

Vesicular Stomatitis
Canine distemper

18
Q

BRSV vs BI3 which is immunosuppressive

A

BRSV

19
Q

Hemagglutinin

A

Antigen on othromyxovirus for attachment and fusion

20
Q

Neuraminidase

A

Antigen on orthomyxovirus for cleaving viral receptors and increase entry of vision and increased transmission

21
Q

In terms of H/N reassortment, what are pigs?

A

Reassortment host

22
Q

What is unique about the CPE in orthomyxoviruses

A

no inclusion bodies

23
Q

Genetic reservoir for influenza? Generation of new subtypes come from this animal

A

Aquatic birds

24
Q

3 SYSTEMS AFFECTED BY CORONA

A

GI, respiratory, CNS

25
Q

Feline corona virus explained with 2 virus names, mutation in ___ and ____ leading to immune mediated ____

A

Feline Enteric coronavirus into feline infectious peritonitis
Because of spike protein change in monocytes and macrophages
Leading to immune mediated vacuities if not cured

26
Q

TGE vs Porcine Epidemic Diarrhea virus

A

Both cause diarrhea and baby pig mortality
TGE is a coronavirus

27
Q

This blunts the intestinal villi of bovines causing diarrhea and less absorption

A

Betacoronavirus Bovine coronavirus

28
Q

The bovine viral diarrhea virus with non cytopathic strain before 150 days results in…

A

Shedding and persistent infection

29
Q

Shedding and persistent infection of BVDV can lead to mucosal disease how

A

with new cytopathic strain added or with a mutation

30
Q

BVDV is from what family

A

Pestivirus ssRNA vertical or horizontal transmission

31
Q

What changes when the Prpc becomes the Prpsc

A

It goes from a alpha helical structure to a beta stealth which is strong and resistant to protease so it accumulates in the neurons

32
Q

Why is a prion not immunogenic?

A

because its a protein not a virus

33
Q

Deer is to Chronic wasting disease as bovine is to

A

Bovine Spongiform encephalopathy (humans can get this too)

34
Q

Oncogenes retrovirus name 2 and how they differ

A

Feline Leukemia (FeLV) and Bovine Leukosis (BLV)