Viral skin (lec 21) Flashcards
Rubeola is?
Route of infection?
measles
Multipl in resp epith/lymph nodes
Spread via monocytes thru blood
Rubeola signs/sxs?
Prodrome: high fever, coryza, cough, conjunctivitis
Koplik’s spots
Rash (starts central)
↑ antibody titers
Rubeola complications?
PNA
Diarr
Encephalitis
Rubeola epidemiology?
humans, monkeys
(U) kids
resp drop transm
Rubeola dx?
rash/Koplik
FA test
Rubeloa vaccine?
MMR II
live
Rubella is?
Presentation?
German measles
mild rash
Rubella complications?
Congenital Rubella Synd:
CV, sight, hearing defects
Rubella vaccine?
MMR
live
HSV disease capacity?
1) invade/replicate in CNS
2) cause latent infections (in dorsal root gangl)
HSV diagnostics?
Tzanck stain
Ballooning pathology
Chickenpox/Shingles caused by?
Varicella-Zoster V
Varicella presentation?
asymmetrical vesicular rash
(follows dermatome)
PRURITIC
viral sxs
Varicella route of infect?
conjunctiva or resp tract mucosa
replicates in lymph nodes -> ºviremia
replicated in liver/spleen -> 2º viremia w/ rash
Varicella epidemiology?
Humans
Winter/Spring
U 5-9 yo
Spread thru resp secretion and vesicles
Varicella tx?
NO ASPRIN (Reyes)
If severe, acyclovir
Shingles caused by?
recrudesce of Zoster
Shingles complications?
neuralgia
Human Herpes Virus 6 (HHV6) causes?
Presentation?
Roseola Infantum/6th disease
High fever followed by rash
HHV6 diagnostics?
EIA (antibody detection)
PCR (DNA detection)
HHV6 tx?
none
no vaccine
Parvovirus B19 causes?
5th Disease/Erythema Infectiosum
5th Disease presentation?
Prodrome w/ mild viral sxs
Rash follows: “slapped cheek”, spares mouth
ADULT: (P) just arthritis w/o prodrome or rash
5th Disease complications?
Rash on limbs/trunk
CT arthralgia: hands/feet, knees, ankles
