Viral infections 3

Question 1

Viral conditions that commonly produce a rash and arthralgia?

Answer 1

Alphaviruses: RRV, BFV

Question 2

Arbovirus definition

Answer 2

Arthropod borne viruses

Question 3

Main clinical syndromes caused by arboviruses?

Answer 3

Fever, rash, arthritis (alphaviruses = RRV, BFV, Chik)
Encephalitis (flaviviruses = MVE)
Haemorrhagic fever (flavi = dengue; and bunya)

Question 4

Life cycle of RRV

Answer 4

Mosquito vector species = Culex and Aedes (same as BFV)

Marsupial reservior

Question 5

Life cycle of BFV

Answer 5

Mosquito vector species = Culex and Aedes (same as RRV)

Question 6

Life cycle Chikungungya

Answer 6

Mosquito vector species = Aedes (same as RRV and BFV)

Monkey reservoir

Question 7

Life cycle of MVE

Answer 7

Mosquito vector species = Culex (same as RRV and BFV)

Bird reservoir

Question 8

Life cycle of dengue

Answer 8

Mosquito vector species = Aedes aegypti

Question 9

Natural history and clinical features of EBV including the cancers associated w EBV

Answer 9

Natural history: usually get the virus in childhood when it is asymptomatic. In adults it can cause glandular fever (infectious mononucleosis) or cancers.

Glandular fever = fatigue, fever, pharyngitis, things to do with mononucleocytes (T and B cells) –> lymphadenopathy, splenomegaly

Cancers = Burkitt’s lymphoma (B cells), Nasopharyngeal carcinoma, Hodgkin’s lymphoma, post-transplant lymphoma