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Block 10 week 4 > Viral Hepatitis- Verma > Flashcards

Viral Hepatitis- Verma Flashcards

1
Q

What is this:
injury to the liver with inflammation of the liver cells

What can cause it?

A

hepatitis

bacteria, drugs, toxins, and excess alcohol, VIRUSES

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2
Q

Viral hepaptitis is caused by which viruses?

A 
Hep A
Hep B
Hep C
Hep D
Hep E
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3
Q

What is the most common liver infection in the US?

A

Viral hepatitis

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4
Q

What types of Hepatitis are transmitted by fecal oral?

A

Hep A and Hep E

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5
Q

What types of hepatitis are transmitted by blood?

A

Hep B, C and D

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6
Q

Acute hepatitis lasts for less than (bank) months. All these viruses can cause acute or short term effects.

A

6 months

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7
Q

Chronic hepatitis lasts for more than (blank) months. Which viruses cause chronic or life-long infections?

A

6 months

-B, C, D

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8
Q

Chronic hepatitis can lead to (blank x 3)

A

cirrhosis, liver failure, liver cancer

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9
Q

What are the ways to get hep A transmission?

A

fecal oral
close personal contact
contaminated food/water
blood exposure (rare)

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10
Q

Hep A is common where?

A

in poor areas with bad hygiene,-> lots of childhood infection

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11
Q

What kind of close personal contact can cause Hep A transmission?

A
  • Household, child day care centers
  • Sexual promiscuity
  • contact with HAV
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12
Q

What 2 types of people will drink or eat contaminated food or water and get Hep A?

A

immigrants or travelers

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13
Q

Hep A accounts for (blank)% of all cases of acute viral hepatitis. Who are at risk to get this?

A 
44%
Persons living in crowded areas
Children./works in day care
Homosexual men
Residents and travelers in underdeveloped countries
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14
Q

Hep E is (common/uncommon) and occurs as a result of travel to developing countries. What groups are at risk?

A

uncommon

persons living in developing nations, refugee camps, overcrosed housing

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15
Q

A 56-year-old Southeast Asian immigrant is diagnosed with chronic hepatitis B virus infection. Considering the epidemiology of this infection in endemic countries, what is the most likely way that this man became infected?

A

Perinatally

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16
Q

A 23-year-old woman presented with an insidious onset of fever, fatigue, joint pain, nausea, anorexia, and abdominal pain. Physical exam revealed hepatomegaly. Serologic tests indicated acute infection with hepatitis B virus. Considering the epidemiology of this disease in the United States, what would the history of the above patient most likely include?

A

unprotected sex with multiple partners

17
Q

How do you characterize Hep B?

A

HBV antigens and host antibodies
HBsAg (surface antigen)
HBcAg (core antigen)
HBe Ag (envelope antigen)

18
Q

What is the first serological marker to rise with Hep B?

A

HBsAG

19
Q

(blank) forms part of the envelope of HBV. Exist in (blank) quantities in the serum.

A

HBsAg

20
Q

What does an HBs Ag positive person indicate?

A

over HBV infection but not necessarily liver disease

21
Q

If you have anti HBsAb then what does this indicate?

A

you have immunity to HBV

22
Q

What will you find in a HBV patient with hep immunity due to natural infection?

A

anti HBc

anti HBs

23
Q

What will you find in a HBV patient with an acute infection?

A

HBsAg
anti IgM
anti HBc

24
Q

What will you find in a HBV patient with a chronic infection?

A

HBs Ag

Anti HBc

25
Q

MSM are at no greater risk of (blank) infection than the general population.

A

HCV

26
Q

What does Anti HBc tell you?
What does anti IgM HBc tell you?
What does HBsAg tell you?
What does anti HBs tell you?

A

exposure
acute exposure
infection
Immunity

27
Q

What kind of virus is Hep C?
How big is it?
How many serotypes?

A

RNA virus
55 nm Diameter
one serotype

28
Q

the 5 year survival in patints with HCC is (blank)

A

less than 5%

29
Q

If you have an Anti HCV positive and HCV RNA positive test, then what does this indicate?

A

acute or chronic HCV depending upon clinical context

30
Q

If you have a positive anti HCV and a negative HCV RNA, then what does this indicate?

A

Resolution of HCV

31
Q

If you have a positive HCV RNA and a negative anti-HCV, the what does it indicate?

A

early acute HCV or chronic HCV in immunosuppressed states

32
Q

If you have negative anti HCV and negative HCV RNA then what does this indicate?

A

Absence of HCV

Block 10 week 4 (10 decks)

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