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Y1 GASTROENTEROLOGY > Viral Hepatitis > Flashcards

Viral Hepatitis Flashcards

1
Q

How is hepatitis A spread?

A

Faeco-oral

Poor hygiene/overcrowding

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2
Q

Hepatitis A is associated with gay men having sex and IV drug users. True/False?

A

True

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3
Q

Does hepatitis A produce chronic infection?

A

No

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4
Q

Which age group has peak incidence of symptoms associated with hepatitis A?

A

Older children - young adults

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5
Q

How is hepatitis A confirmed in the lab?

A

Serology (clotted blood)

Hep A IgM

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6
Q

Hepatitis E is more common than hepatitis A in the UK. True/False?

A

True

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7
Q

How is hepatitis E spread?

A

Faeco-oral
Zoonosis
Person-person in immunocompromised/tropics

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8
Q

Hepatitis D is only found with hepatitis B infection. True/False?

A

True

Exacerbates hepatitis B infection

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9
Q

How is hepatitis B spread?

A

Blood-blood

Sex

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10
Q

Hep B s Ag is present in all hepatitis B -infected individuals. True/False?

A

True

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11
Q

HBsAg present for 4 months indicates chronic infection. True/False?

A

False

Present for > 6 months in chronic infection

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12
Q

Which hepatitis B markers are usually present in highly infectious individuals?

A

Hep B e Ag

Hep B virus DNA

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13
Q

Presence of anti-Hep B IgG indicates acute infection. True/False?

A

False

Presence of anti-Hep B IgM indicates acute infection

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14
Q

How is hepatitis C spread?

A

Blood-blood

Sex (although not as easily as hepatitis B)

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15
Q

Are antivirals given in acute hepatitis?

A

No

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16
Q

Liver cancer is a contraindication for hepatitis treatment. True/False?
What are some other contraindications?

A

True
Cirrhosis
HIV

17
Q

List antivirals used to treat chronic hepatitis infection

A

Adefovir
Entecavir
Tenofovir

18
Q

How is interferon-alpha administered? What else is prescribed?

A

Injection as peginterferon

Ribavirin

19
Q

Peginterferon produces flu-like side effects. True/False?

A

True

20
Q

What are the two options for hepatitis B treatment?

A
  1. Peginterferon alone

2. Antiviral therapy - entecavir, tenofivir

21
Q

What are the symptoms of Hepatitis A?

A 
Fever
Malaise
Anorexia
Nausea
Athralgia
Jaundice
Hepatospleenomegaly
22
Q

How does Hepatitis B differ symptomatically in comparison to Hepatitis A?

A

Increased athralgia and urticaria and has a longer incubation period

23
Q

Anti-Hep B S indicated what about an individual?

A

They are in recovery

24
Q

If a child is infected at birth, what form of hepatitis are they most likely to have?

A

Hepatitis C

Y1 GASTROENTEROLOGY (24 decks)

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