Viral Hepatitis Flashcards

1
Q

What hepatitis viruses are RNA viruses/DNA viruses?

A

All are RNA, except HBV is DNA

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2
Q

What viruses are transmitted via a fecal-oral route?

A

HAV, HEV

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3
Q

List in descending order the most common hepatitis viruses that cause acute hepatitis in the US.

A

HBV, HAV, HCV

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4
Q

What hepatitis viruses never progress to chronic liver dz?

A

HAV, HEV

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5
Q

What hepatitis virus is most likely to result in chronic liver dz?

A

HCV

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6
Q

How is HBV primarily spread?

A

Blood

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7
Q

What hepatitis can spread via vertical transmission?

A

HBV

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8
Q

How is HCV primarily spread?

A

Blood

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9
Q

What is the most common blood borne infection in the US>

A

HCV

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10
Q

In order for HDV to replicate, what prerequisite is necessary?

A

Infection with HBV

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11
Q

What do anti-HAV IgM and anti-HAV IgG indicate?

A

IgM: infection. IgG: recovery/vaccination

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12
Q

What do serum studies that show only HBsAg indicate?

A

Earliest phase of acute HBV

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13
Q

What do serum studies that show HbsAg, HbeAg/HBV DNA indicate, anti-HBc IgM?

A

Acute infection

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14
Q

What do serum studies that show anti-HBc IgG, anti-HBs, and anti-Hbe indicate?

A

Recovered from HBV

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15
Q

What do serum studies that show only anti-HBs IgG indicate?

A

Immunization

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16
Q

What do serum studies that show only HBsAg, anti-Hbe, and anti-HBc IgG indicate?

A

Carrier

17
Q

What do serum studies that show HBsAg, HBeAg/HBV DNA, and anti-HBc IgG?

A

Infective carrier

18
Q

What is the gold standard for diagnosis HCV?

A

PCR

19
Q

What lab findings are characteristic in viral hepatitis?

A

Increased urine UBG/bilirubin, ALT>AST, mixed hyperbilirubinemia

20
Q

What does HBsAg indicate?

A

HBV infection

21
Q

What does anti-HBs indicate?

A

Immunity to HBV

22
Q

What does HBcAg indicate?

A

Core antigen

23
Q

What does anti-HBc IgM indicate?

A

Acute infection

24
Q

What does anti-HBc IgG indicate?

A

Prior exposure or chronic infection

25
Q

What does HBeAg indicate?

A

Indicates active viral replication