Viral Hepatitis Flashcards
Which hepatitis infections can be vaccinated against
A
B
How is hepatitis A transmissioned?
Faecal-oral spread
Give features of hepatitis A
Doesn’t cause chronic disease, is usually benign and self limiting
Flu-like prodrome
RUQ pain
Tender hepatomegaly
Jaundice
Cholestatic liver function tests
How is hepatitis B transmissioned?
Infected blood or body fluids
Vertical transmission from mother to child
What is the intubation period for hepatitis B?
6-20 weeks
Give features of hepatitis B
Fever
Jaundice
Elevated liver transaminases
Give complications of hepatitis B
Chronic hepatitis, ground glass hepatocytes
Liver failure
Hepatocellular carcinoma
Glomerulonephritis
Polyarteritis nodosa
Cryoglobulinaemia
How is hepatitis C transmissioned?
Needle stick injury
Vertical transmission rate from mother to child
Sexual intercourse
How is hepatitis E transmissioned?
Faecal-oral route
Give features of hepatitis E
Shellfish/pork
Summarise hepatitis B antibodies
HBs
- safe, immunisation from vaccine/infection
HBc
- caught, infected previously
HbeAg
- acute, current infectivity
Summarise antibodies
IgM, responds iMMediately
IgG, responds later
