Viral Gastroenteritis/Hepatitis

Question 1

MCC of viral gastroenteritis?

Answer 1

Rotavirus

Question 2

dsRNA, nonenveloped, icosahedral, reovirus?

Answer 2

Rotavirus (Also colitivirus that causes RMSF)

Question 3

ssRNA non-enveloped, icosahedral calcivirus?

Answer 3

Norovirus

Question 4

dsDNA non-enveloped icosahedral virus that causes viral gastroenteritis?

Answer 4

Adenovirus serotypes 40-42

Question 5

Viral gastroenteritis most likely to cause outbreak?

Answer 5

Norovirus

Question 6

Viral gastroenteritis most likely to cause infection in daycare setting?

Answer 6

Rotavirus

Question 7

Viral gastroenteritis that has a vaccine?

Answer 7

Rotavirus

Question 8

Rotavirus VP that binds to gut epithelial cells?

Answer 8

4

Question 9

VP1 does what in rotavirus?

Answer 9

DNA-dependent RNA pol

Question 10

NSP4 does what in rotavirus?

Answer 10

Pore-forming toxin

Question 11

Icosahedral hepatits viruses?

Answer 11

ALL

Question 12

Non-enveloped hepatits viruses?

Answer 12

A and E

Question 13

Enveloped hepatits viruses?

Answer 13

B, C, D

Question 14

+ssRNA picornavirus hepatits viruses?

Answer 14

A

Question 15

+ssRNA calcivirus hepatits viruses?

Answer 15

E

Question 16

Spread via fecal oral route hepatits viruses?

Answer 16

A and E

Question 17

Hepatitis virus that binds HAVCR-1 for cell entry?

Answer 17

A

Question 18

Vaccines available for which hepatitis viruses?

Answer 18

A, B

Question 19

How do you prevent HAV spread?

Answer 19

Chlorination
UV radiation
Formalin

Question 20

Hepatitis virus that has a high risk of mortality in Pregnant women?

Answer 20

E

Question 21

Partially dsDNA hepadnaviridae?

Answer 21

Hep B

Question 22

-ssRNA deltavirus?

Answer 22

Hep D

Question 23

+ssRNA flavivirus?

Answer 23

Hep C

Question 24

Hepatitis that is likely to pass to infant via vertical transmission?

Answer 24

Hep B

Question 25

Dane particle in Hep B does what?

Answer 25

Actual infectious particle?

Question 26

What is the histology of a Hep B infected hepatocyte?

Answer 26

Ground-glass appearance

Question 27

Hep B replication?

Answer 27

Viral DNA pol completes circular DNA
Host DNA poly transcribes RNA
Viral RT re-synthesizes viral DNA

Question 28

What particle is necessary for Hep D infection?

Answer 28

HBsAg to coat Hep Virus

Question 29

Which Hep virus is most likely to progress to chronic hepatitis?

Answer 29

Hep C

Question 30

What receptor does Hep C bind to enter cell?

Answer 30

CD81R and LipoproteinR

Question 31

Which serotype of Hep C is most common is US?

Answer 31

1

Question 32

Which hep c serotypes indicate a better prognosis?

Answer 32

2,3

Question 33

Which hep C serotypes indicate a worse prognosis?

Answer 33

1, 4

Question 34

Yellow fever and Hep G viruses are part of which viral family?

Answer 34

Flavivirus

Question 35

Vaccine available for Yellow-Fever?

Answer 35

Yes

Question 36

Which viral markers would indicate an active infection with Hep B and can be present BEFORE symptoms?

Answer 36

HBV

HBs-antigen

Question 37

Which viral marker would indicate an active infection with Hep B and can be present during ACUTE symptoms?

Answer 37

HBV
HBe-ag
HBs-ag
ANti-Hbc
Anti-HBe

Question 38

Which markers show up during LATE ACUTE phase?

Answer 38

Anti-HBe

Anti-HBc

Question 39

Which markers will be present in a resolved Hep B infection?

Answer 39

Anti-HBc

Anti-HBs

Question 40

Which marker will be present in an indiviudal vaccinated for Hep B?

Answer 40

Anti-HBs

Question 41

Which mark does NOT show up in chronic Hep B infection?

Answer 41

Anti-HBe
Anti-HBc
Anti-HBs