Parasites Flashcards
Protoza vs. Helminths vs. Trematodes?
Protozoa = Unicellular Helminths = Worms Trematodes = FLukles
Most common parasitic infection in US?
Giardia
Who gets Giardia?
Campers/hikers
Fatty, foul-smelling stool?
Giardia
Who gets cryptosporidium?
Water-park people
AIDS worse
Symptoms of cryptosporidium?
Mild, watery diarrhea
Severe if immunocompromised
Who gets Entamoeba histolytica worldwide?
In US?
Tropical slums
US = Gay dudez
Ameiasis symptoms?
Why?
Bloody diarrhea = Amoebic Dysentary
RBC lysis
Serious complication of entamoeba histolytica?
Liver abscess
GI protozoa?
Giardia lamblia
Cryptosporidium parvum
Cyclospora cayetanesis
Entamoeba histolytica
GI Nematodes?
Enterobius vermicularis Strongyloides Ancylostoma Necator Trichuris Ascaris
Nematodes spread by eating eggs?
EAT
Enterobius vermicularis
Ascaris
Trichuris
Nematodes spread by skin contact?
Hookworms (NASty)
Strongyloides
Ancylostoma
Necator
Most common helminth infection?
Enterobius
Anal itch in daycare?
How do you diagnose?
Enterobius
Scotch tape
CANNOT DIAGNOSE FROM STOOL
Helminth found in Large US cities?
Strongyloides
Helminth with possibility of auto-infection?
Strongyloides
10mm hookworm with itchy rash and lethargy?
Why lethargic?
how diagnose?
Ancylostoma/Necator
Fe deficient anemia
EGGS in stool sample
Whipworm?
Trichuris
Bloody diarrhea, iron deficient anemia, progressing to rectal prolapse and finger clubbing?
Trichuris
How DX trichuris?
Barrel-shaped eggs
Largest roundworm?
Ascaris
Symptoms of ascaris?
Usually asymptomatic
Can have intestinal blockage with pain
Lung stage with Charcot-Leyden crystals
Cestodes?
TED (tapeworms)
Taenia
Echinococcus
Diphyllobothrium
Which cestode is spread by eggs in doge feces?
Worst complication?
Such echinococcus
Very liver cysts
Which cestode is spread via larvae in fish?
Diphyllobothrium
How DX diphyllobothrium?
Eggs or proglittids in stool
Which cestode is spread via beef/pork?
Taenia solium
What type of parasite is schistosoma?
Fluke (Trematode)
What causes the symptoms in schistosoma infection?
Immune response
Acute schistosoma symptoms?
Rash, itchy
Chronic schistosoma symptoms?
Pain
Hepatomegaly
Hematura, dysuria
What can be used to treat Giardia infection?
Metronidazole
Nitazoxanide
Paromomycin
TX for cryptosporidium in AIDS patients?
Nitazoxanide
TX for amebic dysentery?
Iodoquinol (Asymptomatic carriers)
Metronidazole
TX for cystoisospora or cyclospora?
TMP-SMX
Which anti-amoeba drug is a Tissue amoebicide?
Metronidazole
Which anti-amoeba drugs are luminal amoebicides?
Iodoquinol
Paromomycin
Nematodes vs. Cestodes vs. Trematodes?
N = Roundworms C = Tapeworms T = Flukes
Which drug kills nematodes and cestodes via targeting b-tubulin formation?
—Bendazole
Which cholinergic anti-helminth targets ALL round worms?
Levamisole
Which cholinergic anti-helminth targets roundworms EXCEPT whipworms (Trichuris)?
Pyrantel Pamoate
Which anti-helminth targets only Ascaris and Strongyloides by binding invertebrate Cl channels and causing paralysis?
Ivermectin
Toxicity of —bendazoles?
Rarely BM
NOT IN PREGNANCY
Toxicity of Cholinergic anti-helminths?
Nausea vomiting
Diarrhea
Toxicity of Ivermectin
Itchy dizziness
Which drug kills cestodes and trematodes?
Praziquantel
Praziquantel mechanism?
Increases permeability to divalent cations
What are treatment options for schistoma infections?
Praziquantel
Steroids (Inflammation response)
What are treatment options for tapeworms?
–Bendazoles
Praziquantel