Viral Diseases Flashcards
1
Q
Polio Virus
A
Poliomyelitis - 99% subclinical - bulbar/paralytic polio % paralysis increase w/ age multiplies in lymphatic tissues incubation 2-3 wks Epidemiology: - Seasonal, summer to fall peak - Fecal-Oral S&S: - Aseptic meningitis - fever - increased WBC in CSF Vaccines: - Salk - Inactive - Sabin - live attenuated Oral Chemotherapy - Passive active immunity
2
Q
Coxsackie A
A
Rash, Colds, Herpangina, HFMD, Aseptic meningitis - V. Stable environmentally Epidemiology: - Seasonal, summer to fall peak - Fecal-Oral S&S: - mucosal rashes - HFMD Diagnostics: - viral isolate, Ab titer, PCR Vaccine: - None Chemo: - None
3
Q
Coxsackie B
A
Visceral tropism, Neonate myocarditis, pleurodynia, orchitis (swollen balls), aseptic meningitis, Rash, Colds, Herpangina, HFMD, - V. Stable environmentally Epidemiology: - Seasonal, summer to fall peak - Fecal-Oral S&S: - neonate myocarditis - pleurodynia - thoracic pain; +++w/ inspiration Diagnostics: - viral isolate, Ab titer, PCR Vaccine: - None Chemo: - None
4
Q
ECHO virus
A
aseptic meningitis, rash - V. Stable environmentally Epidemiology: - Seasonal, summer to fall peak - Fecal-Oral Diagnostics: - viral isolate, Ab titer, PCR Vaccine: - None Chemo: - None
5
Q
EV 70
A
acute hemorrhagic conjunctivitis Epidemiology: - Seasonal, summer to fall peak - Fecal-Oral Diagnostics: - viral isolate, Ab titer, PCR Vaccine: - None Chemo: - None
6
Q
EV 71
A
HFMD and CNS infections Epidemiology: - Seasonal, summer to fall peak - Fecal-Oral Diagnostics: - viral isolate, Ab titer, PCR Vaccine: - None Chemo: - None
7
Q
HAV
A
Hepatitis A Epidemiology: - Fecal-Oral S&S: - anorexia, jaundice, fever, nausea Diagnostics: - viral isolate, Ab titer, PCR, LFTs Vaccine: - killed Chemo: - passive IVIg
8
Q
Rhinovirus
A
Common Cold Epidemiology: - Winter Peak - Aerosol S&S: - symptoms of a fucking cold Diagnostics: - Tracheal culture Vaccine: - None; too many serotypes Chemo: - supportive
9
Q
Reovirus/Rotavirus
A
Gastroenteritis, infant diarrhea "Rio de Janeiro poops" Epidemiology: - Winter Peak - Fecal-Oral S&S: - diarrhea Vaccine: - Live Attenuated - Rotarix, RotaTeq Chemo: - supportive, ORT
10
Q
Adenovirus (Fecal-Oral)
A
Gastroenteritis, infant diarrhea Incubation 3-10 days Epidemiology: - 0-24mo prim. diarrhea cause S&S: - diarrhea Chemo: - supportive, ORT
11
Q
Adenovirus (Airborne)
A
Epidemic keratoconjunctivitis
Pinkeye
Stable when dried
12
Q
Norovirus
A
Gastroenteritis Epidemiology - high density, e.g. ships, nursing homes, camps, prisons - O type blood more susceptible - Fecal-Oral