Viral Diseases Flashcards

1
Q

Polio Virus

A
Poliomyelitis
- 99% subclinical
- bulbar/paralytic polio
% paralysis increase w/ age
multiplies in lymphatic tissues
incubation 2-3 wks
Epidemiology:
- Seasonal, summer to fall peak
- Fecal-Oral
S&S:
- Aseptic meningitis
- fever
- increased WBC in CSF
Vaccines:
- Salk - Inactive
- Sabin - live attenuated Oral
Chemotherapy
- Passive active immunity
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2
Q

Coxsackie A

A
Rash, Colds, Herpangina, HFMD, Aseptic meningitis
- V. Stable environmentally
Epidemiology:
- Seasonal, summer to fall peak
- Fecal-Oral
S&S:
- mucosal rashes
- HFMD
Diagnostics:
- viral isolate, Ab titer, PCR
Vaccine:
- None
Chemo:
- None
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3
Q

Coxsackie B

A
Visceral tropism, Neonate myocarditis, pleurodynia, orchitis (swollen balls), aseptic meningitis, Rash, Colds, Herpangina, HFMD,
- V. Stable environmentally
Epidemiology:
- Seasonal, summer to fall peak
- Fecal-Oral
S&S:
- neonate myocarditis
- pleurodynia
- thoracic pain; +++w/ inspiration
Diagnostics:
- viral isolate, Ab titer, PCR
Vaccine:
- None
Chemo:
- None
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4
Q

ECHO virus

A
aseptic meningitis, rash
- V. Stable environmentally
Epidemiology:
- Seasonal, summer to fall peak
- Fecal-Oral
Diagnostics:
- viral isolate, Ab titer, PCR
Vaccine:
- None
Chemo:
- None
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5
Q

EV 70

A
acute hemorrhagic conjunctivitis
Epidemiology:
- Seasonal, summer to fall peak
- Fecal-Oral
Diagnostics:
- viral isolate, Ab titer, PCR
Vaccine:
- None
Chemo:
- None
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6
Q

EV 71

A
HFMD and CNS infections
Epidemiology:
- Seasonal, summer to fall peak
- Fecal-Oral
Diagnostics:
- viral isolate, Ab titer, PCR
Vaccine:
- None
Chemo:
- None
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7
Q

HAV

A
Hepatitis A
Epidemiology:
- Fecal-Oral
S&S:
- anorexia, jaundice, fever, nausea
Diagnostics:
- viral isolate, Ab titer, PCR, LFTs
Vaccine:
- killed 
Chemo:
- passive IVIg
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8
Q

Rhinovirus

A
Common Cold
Epidemiology:
- Winter Peak
- Aerosol
S&S:
- symptoms of a fucking cold
Diagnostics:
- Tracheal culture
Vaccine:
- None; too many serotypes
Chemo:
- supportive
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9
Q

Reovirus/Rotavirus

A
Gastroenteritis, infant diarrhea
"Rio de Janeiro poops"
Epidemiology:
- Winter Peak
- Fecal-Oral
S&S:
- diarrhea
Vaccine:
- Live Attenuated
- Rotarix, RotaTeq
Chemo:
- supportive, ORT
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10
Q

Adenovirus (Fecal-Oral)

A
Gastroenteritis, infant diarrhea
Incubation 3-10 days
Epidemiology:
- 0-24mo prim. diarrhea cause
S&S:
- diarrhea
Chemo:
- supportive, ORT
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11
Q

Adenovirus (Airborne)

A

Epidemic keratoconjunctivitis
Pinkeye
Stable when dried

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12
Q

Norovirus

A
Gastroenteritis
Epidemiology
- high density, e.g. ships, nursing homes, camps, prisons
- O type blood more susceptible 
- Fecal-Oral
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