Viral and Chlamydial Respiratory Tract Infections Flashcards
weakness/paralysis similar to poliovirus, non-polio enteroviruses and West nile virus =
acute flaccid myelitis
What two syndromes are associated with complications of flu infection (other than pneumonia)
- Reyes syndrome
2. Guillain-Barre syndrome
Which form of chlamydiae is the infectious, nongrowing form responsible for dispersal
Elementary body
What is the major form of transmission of rhinovirus?
hands = vector in person-to-person transmission
aerosol and fomites possible
Which form of chlamydiae is the growing/vegetative form
reticulate body
What make chlamydiae act like a virus?
What makes it act like a bacteria?
virus = energy parasite, obligate intracellular parasite bacteria = binary fission
What are the two forms chlamydiae assumes
- elementary body (spore like)
2. reticulate body (growing/vegetative form)
antigenic subtypes of the flu are based on :
envelope proteins
What is different about giving a flu vaccine to a child versus and adult
children under 9 need TWO ADMINISTRATIONS
How long is immunity to rhinovirus?
What is this referred to as?
18 months
“transient” immunity
What age group has the greatest incidence of rhinovirus in the winter
children and young adults
What specifically happens during an antigenic drift of the influenza virus
point mutations of H or N proteins
What is in a Quadrivalent form of a flu vaccine
2 type A viruses
2 type B viruses
Why can the influenza virus go through antigenic shift and drift easily while other viruses cannot
segmented genome
What is the major reservoir for flu virus
avian
What specifically happens during an antigenic shift of the influenza virus
recombination involving entire genome segments encoding H or N gene
*implies mixed infections occur
What is the #1 adverse effect of the flu vaccine
pain at the site of injection
Which cells are more heavily infected with a cold (ARD)
cells lining nasal passage and pharynx
The three types of flu (A, B, and C) are defined by:
nucleocapsid proteins
What does the “N” stand for in naming flus
neuraminidase (viral penetration and release from infected cells)
What does the “H” stand for in naming flus
H hemagglutinin (viral attachment)
What are the four potential viruses associated with a cold (ARD)
rhinovirus
coronavirus
adenovirus
“unknown virus”
How are flu vaccines grown
inside of embryonated chicken eggs
What type of flu vaccine can you give to elderly patients to increase immune response
high potency and adjuvanated
Which type of flu is the worst
type A
type B can also cause epidemics and C is weak
Chlaymidae trachomatis can cause what respiratory infection
infant pneumonia
Chlamydiae pneumonia is most associated with:
atherosclerosis
Chlamydiae trachomatis in an infant usually goes to which type of tissue
ocular
Regarding the flu, what is the thing that actually kills patients
secondary pneumonia
watch out for “Return of fever”
***he made a big point of this in the lecture and told us to “add it to our notes”
