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MSK 2 > Vicki Radiology > Flashcards

Vicki Radiology Flashcards

1
Q

15 year old male with increasing left upper arm pain of 3mo duration. Recent onset of low grade fever. Local tenderness and it extends into soft tissue. What tumor? And name the genetics.

A

t(11,22) causing fusion protein EWS-FLI1 - ewing Sarcoma

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2
Q

p53 damage

A

osteosarcoma, Li Fraumeni

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3
Q

bone decreased bloody supply

A

avascular necrosis/osteonecrosis

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4
Q

failure of normal bone resportion due to defective osteoclasts

A

osteopetrosis

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5
Q

**diaphysis lesions

A

ewing, myeloma, osteoid osteoma

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6
Q

**metaphysis lesions

A

osteosarcoma, osteochondroma

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7
Q

**epiphysis lesions

A

giant cell tumor

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8
Q

decreased cortical thickening

A

osteoporosis

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9
Q

diffuse, dense bone

A

osteopetrosis

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10
Q

thickening of calvarium

A

osteitis deformans (Paget dz of bone)

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11
Q

XR shows irregular lucencies with adjacent sclerosis

A

osetonecrosis

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12
Q

MRI shows dark serpingious necrotic bone

A

osetonecrosis

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13
Q

bamboo spine

A

ankylosing spondylitits

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14
Q

XR shows soap bubble appearance

A

giant cell tumor

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15
Q

XR shows exotosis of bone

A

osteochondroma

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16
Q

XR shows “sunburst pattern”/”Codman” Triangle around metaphysis of long bones

A

osteosarcoma

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17
Q

Best test for soft tissue involvement (malignancy).

A

MRI

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18
Q

Anaplastic small blue cell tumor

A

Ewing Sarcoma

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19
Q

XR shows “onion skin” around diaphysis of long bone

A

ewing sarcoma

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20
Q

What cancers have blue cells?

A 
MR. LEMONS
Melanoma
Rhabdomyosarcoma
Lymphoma
Ewing
Medulloblastoma
Other 
Neuroblastoma 
Small Cell (oat cell)
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21
Q

32 year old male with a hx of and current presentation of multiple fractures after tripping. Slight weakness in facial mm and decreased hearing on left. On XR, see bright bone/lucent bone.

A

Osteopetrosis (CAnhydrase mutation - super dense outside, bone widening)

22
Q

Spongiosa filling the medullary canal with no mature trabeculae

A

osteopetrosis

23
Q

trabecular thinning with fewer connections

A

osteoporosis

24
Q

lamellar bone structure resembling mosaic

A

paget disease

25
Q

In osteopetrosis, what manifestation causes pancytopenia?

A

Bone fills marrow space

26
Q

What artery supplies the head of the femur? Results of insufficiency of this artery.

A

Medial circumflex femoral artery - insufficiency causes osteonecrosis (avascular necrosis).

27
Q

Main causes of osteonecrosis

A

CS (also fx, sickle cell, alcoholism, pancreatitis, Legg-Calve perthes disease)

28
Q

XR shows crescent sign (dead bone)

MRI shows rim sign (fluid between sclerotic borders)

A

osteonecrosis

29
Q

Patients with primary malignant and benign bone tumors present with pain, swelling, and occasionally pathologic fracture of the involved bone. Biopsy shows non-neoplastic osteoclasts and their precursors.

A

Giant cell tumor (osteoclastoma)

30
Q

increased ostoid

A

osteoid osteoma, osteoblastoma, giant cell tumor

31
Q

what is one of the only bone tumors that occurs at the epiphysis?

A

giant cell tumor (osteoclastoma) in the femur or tibia

32
Q

if giant cell tumor (osteoclastoma) mets, where will it go 3% of the time?

A

lungs

33
Q

osteoclast dysfunction

A

Osteitis deformans (Paget disease of bone)

34
Q

osteoblast dysfunction

A

osteoporosis

35
Q

defective mineralization of osteoid

A

osteomalacia

36
Q

infarction of bone and marrow

A

osteonecrosis

37
Q

> 50 years old. patients experience pain, skeletal deformity, neurological symptoms, pathologic fractures, increased hat size, increased output heart failure, osteosarcoma, bowed tibia and deafness (due to narrowing of auditory foramen).

A

Osteitis deformans (Paget disease of bone)

38
Q

XR shows a 14 year old boy with a densly sclerotic lesion in distal femur extending form growth plate into diaphysis. (so the metaphysis). What is this cancer and what is the term for when the periostium lifted, forming angle with the cortex

A

Codman’s triangle,

osteosarcoma

39
Q

20yo male with painless, hard subcutaneous mass in popliteal fossa that is cartilage-capped.

A

osteochondroma

40
Q

osteochondroma can transform into ___

A

chondrosarcoma (Malig)

41
Q

osteochondromas develop in bones of ___ origin in the ____

A

*endochondral origin in the *metaphysis near growth pate of long tubular bone

42
Q

Both MCP joint of a 37yo woman were swollen and tender. Early morning stiffness. She is likely to have…

A

Pannus formation. (this is Rheumatoid arthritis).

43
Q

DIP and PIP - what arthritis and what nodes?

A

Osteoarthritis
DIP=Herberden nodes
PIP=bouchard nodes

ossociate with osteophytes and subchondral cysts

44
Q

Hitchhikers thumb deformity, ulnar deviation and boutonniere and swan neck.

A

Rheumatoid Arthritis

45
Q

• Most commonly affects boys

A

Ewing Sarcoma

46
Q 
▫ Sandwich vertebrae: dense bands
of sclerosis parallel to endplates
▫ Bone widening
▫ Erlenmeyer flask deformity of
tubular bones
• Medullary encroachment
A

AD adult B9 ostepetrosis

47
Q

MRI: ▫ Heterogeneous signal intensity with low to intermediate intensity
▫ Focal cystic areas
▫ Low-signal intensity pseudocapsule

A

Giant cell tumor

48
Q

Skull deformities
▫ Diploic thickening of inner and outer calvarium
▫ Cotton wool appearance: mixed lytic and sclerotic lesions
▫ Frontal bone enlargement

A

Paget disease

49
Q

**Develop only in bones of endochondral origin
and arise from the metaphysis near the growth
plate of long tubular bones.
• This tumor is are slow growing tumors and can present as painful if they impinge on a nerve or if the stalk is fractured.

A

Osteochondroma

50
Q

herberden nodes, bouchard nodes, subchndral cysts

A

osteoarthritis

51
Q

pannus formation

A

rheumatoid arthritis

MSK 2 (14 decks)

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