Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pathology Flashcards > VI - Neoplasia > Flashcards

VI - Neoplasia Flashcards

1
Q

Pathology Flashcards

This term literally means “new growth”.

A

Neoplasia(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Pathology Flashcards

An abnormal mass of tissue the growth of which exceeds and is uncoordinated with that of the normal tissues and persists in the same excessive manner after the cessation of stimuli which evoked the change.

A

Neoplasm(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Pathology Flashcards

Study of tumors.

A

Oncology(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pathology Flashcards

Benign or malignant?Localized

A

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Pathology Flashcards

Benign or malignant?Amenable to surgical removal

A

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Pathology Flashcards

Benign or malignant?Invades and destroys adjacent tissues.

A

Malignant(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Pathology Flashcards

What are the two basic components of tumors?

A

Parenchyma and Stroma(TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Pathology Flashcards

Benign or malignant?Metastasis

A

Malignant(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pathology Flashcards

This component of tumors largely determines its biologic behavior.

A

Parenchyma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pathology Flashcards

This component of tumors determines the name of the growth.

A

Parenchyma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pathology Flashcards

This component of tumors is crucial to the growth of neoplasms since it carries the blood supply and provides support to the growth of cells.

A

Stroma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Pathology Flashcards

Benign or malignant?Fibroma

A

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Pathology Flashcards

Benign or malignant?Chondroma

A

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Pathology Flashcards

Benign or malignant?Adenoma

A

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Pathology Flashcards

Benign or malignant?Hepatoma

A

Malignant(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Pathology Flashcards

Benign or malignant?Papilloma

A

Benign(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Pathology Flashcards

Malignant neoplasms arising in mesenchymal tissue or its derivatives.

A

Sarcomas(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Pathology Flashcards

Benign tumor arising in fibrous tissue is called?

A

Fibroma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Pathology Flashcards

A benign cartilagenous tumor is called?

A

Chondroma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Pathology Flashcards

This is a benign epithelial neoplasm which produces glandular patterns or neoplasms derived from glands but not necessarily exhibit glandular patterns

A

Adenoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Pathology Flashcards

These are benign epithelial neoplasms, growing on any surface that produce microscopic or macroscopic finger-like fronds.

A

Papillomas(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.174

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Pathology Flashcards

A mass that projects above a mucosal surface to form a macroscopically visible structure.

A

Polyps(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Pathology Flashcards

A cancer of fibrous tissue origin.

A

Fibrosarcoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Pathology Flashcards

Malignant neoplasms of epithelial cell origin.

A

Carcinoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.175

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Pathology Flashcards

Carcinoma of squamous cell origin.

A

Squamous cell carcinoma(TOPNOTCH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Pathology Flashcards

Carcinoma of squamous cell origin.

A

Squamous cell carcinoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Pathology Flashcards

Benign or malignant?Lymphoma

A

Malignant(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Pathology Flashcards

Benign or malignant?Seminoma

A

Malignant(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Pathology Flashcards

The extent to which neoplastic cells resemble their normal forebears morphologically and functionally.

A

Differentiation(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.176

30
Q

Pathology Flashcards

This is considered a hallmark of malignancy, which literally means “to form backward”.

A

Anaplasia(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.177

31
Q

Pathology Flashcards

These cells display marked pleomorphism, nuclei are variable and bizzare in size and shape. Chromatin is course and clumped. Mitoses are often numerous and distinctly atypical.

A

Anaplastic cells(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.177

32
Q

Pathology Flashcards

This term is defined by disorderly but non-neoplastic proliferation of cells, described as a loss in uniformity of individual cells and in their architectural orientation.

A

Dysplasia(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.178

33
Q

Pathology Flashcards

Defined as dysplactic changes which involve the entire thickness of the epithelium.

A

Carcinoma -in - situ(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.178

34
Q

Pathology Flashcards

True or false?Dysplasia always progress to cancer.

A

False(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.178

35
Q

Pathology Flashcards

True or false?Lack of capsule in a neoplastic growth indicates malignancy.

A

FalseSome benign tumors are not encapsulated.(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.179

36
Q

Pathology Flashcards

This term describes the development of secondary implants discontinuous with the primary tumor, in remote tissues.

A

Metastasis(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.179

37
Q

Pathology Flashcards

Next to metastasis, this is the most reliable feature that distinguishes malignant from benign tumors.

A

Local invasiveness(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.179

38
Q

Pathology Flashcards

Methods of dissemination of malignant neoplasms? (3)

A

SeedingLymphatic spreadHematogenous spread(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.180

39
Q

Pathology Flashcards

This is the mode of dissemination of cancers of the ovary and CNS.

A

Spread by seeding(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.180

40
Q

Pathology Flashcards

This is the mode of dissemination more typical of carcinomas.

A

Lymphatic spread(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.180

41
Q

Pathology Flashcards

This is the mode of dissemination more typical of sarcomas.

A

Hematogenous spread(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.180

42
Q

Pathology Flashcards

It is defined as the first lymph node in a regional lymphatic basin that receives lymph flow from a primary tumor.

A

Sentinel lymph node(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.180

43
Q

Pathology Flashcards

What are the most common sites of metastasis involved in hematogenous dissemination of cancer?

A

Liver and lungs(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.181

44
Q

Pathology Flashcards

This substance is a byproduct of metal smelting, a component of alloys, electrical and semiconductor devices which could cause cancer of the lungs and skin and hemangiosarcomas.

A

Arsenic and its compounds(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.183

45
Q

Pathology Flashcards

This substance was formerly used for fire-resistant textiles and construction materials which could cause lung cancer and more prominently malignant mesothelioma

A

Asbestos(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.183

46
Q

Pathology Flashcards

This substance is commonly used as a solvent in paint, rubber, dry cleaning, adhesives and detergents which could cause leukemias and Hodgkin lymphoma.

A

Benzene(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.183

47
Q

Pathology Flashcards

This substance is used as hardener for metal alloys used in aerospace applications and nuclear reactors which is commonly associated with cancer of the lung.

A

Beryllium and its compounds(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.183

48
Q

Pathology Flashcards

This substance is used in solders, batteries and metal alloys commonly associated with cancers of the prostate.

A

Cadmium and its compounds(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.183

49
Q

Pathology Flashcards

This substance is a refrigerant and used as adhesive for plastics, which causes hepatic angiosarcoma.

A

Vinyl chloride(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.183

50
Q

Pathology Flashcards

Inherited gene : Cancer syndromeRB gene :__________

A

Retinoblastoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.184

51
Q

Pathology Flashcards

Inherited gene : Cancer syndromep53 : ______________

A

Li Fraumeni Syndrome(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.184

52
Q

Pathology Flashcards

Inherited gene : Cancer syndrome__________ : Familial Adenomatous Polyposis / Colon CA

A

APC Gene(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.184

53
Q

Pathology Flashcards

Inherited gene : Cancer syndrome_________ : Breast on Ovarian Tumors

A

BRCA 1 gene(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.184

54
Q

Pathology Flashcards

Inherited gene : Cancer syndrome_________ : Breast Cancer only

A

BRCA 2 gene(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.184

55
Q

Pathology Flashcards

Inherited gene : Cancer syndromeRET gene : _________

A

Multiple Endocrine Neoplasia 1 and 2(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.184

56
Q

Pathology Flashcards

Inherited gene : Cancer syndrome__________ : Colon cancer

A

kras gene(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.184

57
Q

Pathology Flashcards

Normal cellular genes whose products promote cell proliferation.

A

Proto-oncogenes(TOPNOTCH)

58
Q

Pathology Flashcards

Normal cellular genes whose products promote cell proliferation.

A

Proto-oncogenes(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.188

59
Q

Pathology Flashcards

It is a naturally occurring carcinogenic agent produced by some strains of Aspergillus, a mold that grows on improperly stored grains and nuts.

A

Aflatoxin B(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.209

60
Q

Pathology Flashcards

There is a strong correlation between the dietary level of Aflatoxin and what type of cancer?

A

Hepatocellular Carcinoma(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.209

61
Q

Pathology Flashcards

These substances require metabolic conversion to be carcinogenic.

A

Indirect - acting carcinogens(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.209

62
Q

Pathology Flashcards

These substances stimulate proliferation of the mutated cells.

A

Promoters(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.210

63
Q

Pathology Flashcards

How does ionizing radiation cause cancer?

A

Through chromosome breakage, translocations and point mutations leading to genetic damage and carcinogenesis.(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.210

64
Q

Pathology Flashcards

What is the mechanism of action of UV rays in the formation of neoplastic cells?

A

UV rays induce formation of pyrimidine dimers within DNA leading to mutations.(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.210

65
Q

Pathology Flashcards

This is the only retrovirus that has been demonstrated to cause cancer in humans.

A

Human T-cell Leukemia Virus -1 (HTLV-1)(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.211

66
Q

Pathology Flashcards

HPV strains which has been implicated in the genesis of cervical and anorectal cancer.

A

HPV 16, 18(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.212

67
Q

Pathology Flashcards

EBV has been implicated in the pathogenesis of the following cancers except:A. Burkitt lymphomaB. Lymphoma in HIV patientsC. Nasopharyngeal carcinomaD. Hodgkin lymphomaE. None of the above

A

E. none of the above(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.212

68
Q

Pathology Flashcards

Which hepatitis virus leads to hepatocellular carcinoma?

A

HBV, HCV(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.213

69
Q

Pathology Flashcards

This is the first bacterium to be classified as a carcinogen.

A

Helicobacter pylori(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.213

70
Q

Pathology Flashcards

What type of cancer can be caused by H.pylori?

A

Gastric adenocarcinoma Gastric MALT lymphomas(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.214

71
Q

Pathology Flashcards

These are benign epithelial neoplasms, growing on any surface that produce microscopic or macroscopic finger-like fronds.

A

Papillomas(TOPNOTCH)

72
Q

Pathology Flashcards

Tumor antigens are presented on the cell surface by MHC Class I molecules to which type of T lymphocytes?

A

CD8+ T lymphocytes(TOPNOTCH)Robbins Basic Pathology, 8th Ed p.215

Pathology Flashcards (23 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions