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PART 1 > Vessel development > Flashcards

Vessel development Flashcards

1
Q

what embryonic layer gives rise to the endothelial cells and the blood cells

A

the mesoderm

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2
Q

What are blood cells derived from?

A

Endothelial cells

Haemangioblasts

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3
Q

What are mural cells (SMCs/Pericytes) derived from?

A

Neural crest or mesoderm

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4
Q

What activates VEGF expression

A

Hypoxia inducible factor 1 alpha (HIF1a)

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5
Q

How does HIF1a work

A

HIF1a gets uniquinated and degraded - von hippel lindau protein targets it for ubiquination - a proxyl hydroxylase binds

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PART 1 (11 decks)

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