Ocular surface Flashcards

1
Q

What are the 3 layers of the tear film?

A

Lipid layer, aqueos layer, mucin layer

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2
Q

What produces lipid, aqueous and mucin

A

Lipid –> meibomian glands
Aqueous ==> lacrimal gland
Mucin –> goblet cells

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3
Q

What are three parts of the conjunctive?

A

Palpebral conj,
Bulbar conj.
Forniceal conj.

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4
Q

What are the layers of the cornea?

A
Epithelium 
Bowman's layer
Stroma 
Descemet's membrane 
Endothelium
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5
Q

Layers of epithelium of cornea? (3)

A
Superficial cells 
Middle zone (wing cells) 
Basal cells (stains with periodic acid)
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6
Q

What do dermatan sulphate and keratan sulphate do?

A

Bind to colleagen at specific points to regulate fibril spacing and thickness of interfibrillar space

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7
Q

What do dermatan sulphate and keratan sulphate do?

A

Bind to colleagen at specific points to regulate fibril spacing and thickness of interfibrillar space

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8
Q

in corneal endothelium, what cell density causes oedema,swelling ettc

A

<800 cells/mm2

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9
Q

How many cells are required for transplantation

A

1500/mm2 in a donor is too low for transplantation

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10
Q

What is the sensory supply to the cornea?

A

V1 –> long ciliary nerves –> annular plexus near limbus –> form a subepithelial plexus after losing their myelin sheath –> Intraepithelial plexus

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11
Q

Iris divided into 2 via?

A

collarette

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12
Q

Iris sympathetic/parasympathetic supply?

A

sympatheic –> long ciliary neres

parasympathetic –> short ciliary nerves

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13
Q

Type of Collagen found in iris?

A

Type 1 and 3

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14
Q

• Ciliary body dis-insertion from scleral wall is called??

A

ciliary body cleft

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15
Q

• Pilocarpine lowers IOP via?

A

contraction of longitudinal muscles of ciliary body causes distrention of the inter and intra trabecular spaces of the trabecular meshwork and lowers IOP

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16
Q

• Rods to cone ratio?

17
Q

Most retinal cell nuclei lay in what layer?

A

OUTER NUCLEAR LAYER

18
Q

• Components of the blood retinal barrier

A

Outer BRB - tight junctions b/w ONL

Inner BRB - junctions b/w retinal vessel endothelium

19
Q

What are the main collagen types in following tissue?

Sclera ———–
Lens capsule ———–
Vitreous ———–

A

Sclera ———– 1 and 3
Lens capsule ———– 4
Vitreous ———– 2

20
Q

Where is the thinnest part of sclera? Why is it important?

A

Behind recti/EOM insertio. Forms a frequent site of scleral rupture following trauma

21
Q

What is the blood supply of rectus muscles? Which one has

only one blood supply?

A

Anterior ciliary artery

The lateral rectus has one associated anterior ciliary artery

22
Q
Refraction power (dioptre) of
 eye ------
 lens ------
 air-tear +43.6 D
 tear-cornea +5.3 D
 cornea-aqueous -5.8 D
A

eye —— 58 D

lens —— 15 - 18 D

23
Q
Refractive index of
 lens ------
 vitreous ------
 air 1
 tear 1.336
 aqueous Humor 1.336
 cornea 1.376
A

lens —— 1.406 (nucleus). 1.36 (cortex)

vitreous —— 1.33

24
Q

Three layers of tear film?

A

Mucin
Aqueos
lipid

25
What cells in conjunctiva produce mucin?
Goblet cells
26
what is a pterygium?
benign growth of the conjunctiva characterized by elastotic degenration of collagen
27
What are the two processses that contribute to corneal deturgescence?
evaporation of the surface and the corneal epithelial pump
28
What is the normal endothelial cell count of the cornea at birth and at 40 years of age?
Birth : 3000 - 4000 cells / mm2 | 40 years: 2,500 cells / mm2