Ventilation and Control of Breathing Part 1 Flashcards
Which 3 structures are in the respiratory zone
Respiratory bronchioles
Alveolar ducts
Alveolar sacs
Flow and pressure in the lungs
Flow is high (entire CO from RV)
Pressure is low (25/8 mmHg)
Ventilation depends on which 3 pressures
Atmospheric
Alveolar
Intrapleural
2 main inspiration muscles
Diaphragm (main one)
External intercostals
Accessory muscles for
- Inspiration
- Expiration
- Scalenes, sternocleidomastoids
2. Abdominal muscles, internal intercostals
Atelectasis
Alveolar collapse
3 mechanical factors affecting ventilation
Surface tension of alveolar fluid
Compliance of lungs
Airway resistance
Surfactant
Mix of phospholipids and protein
Secreted by type 2 alveolar cells
Lowers surface tension = increases compliance
Secretion stimulated by deep breaths
Law of LaPlace
P = 2T/r
Without surfactant, air would flow from small alveoli into large ones and the small ones would collapse
Minute ventilation
How much air gets to the alveoli in a minute
V = tidal volume x resp rate
Volumes:
- Tidal
- IRV
- ERV
- RV
- 500 mL
- 3000 mL
- 1000 mL
- 1200 mL
Capacities:
- Inspiratory capacity
- Vital capacity
- FRC
- Total LC
- Vt + IRV = 3500 mL
- Vt + IRV + ERV = 4500 mL
- ERV + RV = 2200mL
- Vt + ERV + IRV + RV = 5700 mL
What measurement can you not get with spirometry
Residual volume
And therefore not total lung volume either