Vasopressors Flashcards
1
Q
What class of medication is phenylephrine?
A
Alpha-adrenergic agonist
2
Q
What does phenylephrine treat?
A
Peri-operative hypotension and shock
3
Q
What is the typical IV bolus dose of phenylephrine for hypotension?
A
400-100 mcg/dose; may be repeated-not to exceed 200 mcg
4
Q
What is the typical IV continuous infusion dose of phenylephrine for hypotension?
A
start at 10-35mcg/min and titrate to BP goal (not to exceed 200 mcg/min)
5
Q
True or false: Acidosis may reduce efficacy of phenylephrine
A
True
6
Q
What are the adverse effects of phenylephrine?
A
- reflex bradycardia
- hypertension
- peripheral vasoconstriction and ischemia
- low cardiac output
- metabolic acidosis
- dyspnea/respiratory distress
- decreased urine output
- IV extravasation/necrosis
7
Q
What is the antidote for phenylephrine IV extravasation?
A
Phentolamine
8
Q
What is the onset of action of phenylephrine?
A
1-3 minutes
9
Q
What is the duration of action of phenylephrine?
A
5-20 minutes
