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31 Hypothalamic and pituirary drugs > Vasopressin and related drugs > Flashcards

Vasopressin and related drugs Flashcards

1
Q

Vasopressin related drugs (3 drugs)

A

Desmopressin
Conivaptan
Tolvaptan

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2
Q

Desmopressin - MOA

A

Activates renal V2 receptors: Increased water reabsorption (by insertion of aquaporins).
Expands ECF volume, concentrates urine.

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3
Q

Desmopressin - indications

A

Enuresis (diabetes insipidus, children)
Von Willebrand disease and hemophilia
Controlling bleeding in varices and diverticula

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4
Q

Desmopressin - caution in which group of patients?

A

Pt with coronary artery disease

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5
Q

Overdose of desmopressin can cause

A

Dilutional hyponatremia

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6
Q

Drug used for hyponatremia in hospitalized patients

A

Conivaptan

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7
Q

Administration of conivaptan

A

IV only

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8
Q

Tolvaptan - indications

A

Hyponatremia (heart failure, cirrhosis, SIADH)

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31 Hypothalamic and pituirary drugs (4 decks)

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