Corticotropin, TSH, prolactin, oxytocin related drugs

Question 1

Corticotropins - 3 drugs

Answer 1

Porcine corticotropin
Cosyntropin
Corticorelin ovine triflutate

Question 2

Corticotropins - MOA

Answer 2

Increased conversion of cholesterol to pregnenolone. Stimulates of adrenal cortex to produce: cortisol, aldosterone, and androgens

Question 3

Which drug is used to diagnose the cause of adrenal insufficiency?

Answer 3

Cosyntropin

Question 4

Corticorelin ovine triflutate - indications

Answer 4

Diagnostic for Cushing disease (pituitary adenoma vs adrenal tumor)

Question 5

Tyrotropin alfa - indications

Answer 5

Diagnosis of thyroid disorders

Follow-up evaluation after thyroid cancer

Question 6

Prolactin inhibitors (1 group + 2 examples)

Answer 6

Dopamine D2 agonists: cabergoline, bromocriptine

Question 7

Drugs indicated for hyperprolactinemia (2 drugs)

Answer 7

Cabergoline

Bromocriptine

Question 8

Drug used for mixed GH+prolactin pituitary adenoma

Answer 8

Cabergoline

Question 9

Bromocriptine - indications

Answer 9

Prolactinemia

Parkinson

Question 10

Dopamine D2 agonists - adverse effects

Answer 10

Psychiatric effects.

Erythromelagia

Question 11

Oxytocin - indications + administration

Answer 11

Induce labor
Milk let-down - nasal spay
Postpartum bleeding - IM

Question 12

Oxytocin - contraindications

Answer 12

Fetal distress
Abnormal fetal presentation
Prematurity
Cephalopelvic disproportion

Question 13

Oxitocin should not be combined with (and why)?

Answer 13

Vasopressors - cause severe hypertension