Vasculitis

Question 1

Name one type of vasculitis that affects the small vessels

Answer 1

Henoch-Schonlein purpura- HSP
Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss syndrome)
Microscopic polyangiitis
Granulomatosis with polyangiitis (Wegner’s)

Question 2

Name one type of medium sized vasculitis

Answer 2

Polyarteritis nodosa

Kawasaki Disease !!!!!!

Question 3

Name one large vessel type vasculitis

Answer 3

GCA
Takayasu’s arteritis

Question 4

List three aspects of the presentation of vasculitis

Answer 4

purpura
joint and muscle pain
peripheral neuropathy
renal impairment
anterior uveitis and scleritis
hypertension
GI disturbance

Question 5

List two systemic features of vasculitis

Answer 5

fatigue
fever
weight loss
anorexia
anaemia

Question 6

What is the main blood test for vsaculitis?

Answer 6

ANCA

Question 7

What is the management of vasculitis

Answer 7

steroids- oral, IV, nasal, inhaled
Immunosuppressants- methotrexate, azathioprine

Question 8

Which vasculitis might inhaled steroids be useful for?

Answer 8

churg-strauss syndrome= eosinophilic GPA

Question 9

Name one vasculitis that typically affects children

Answer 9

Kawasaki disease
HSP

Question 10

What is the typical dermatological distribution of HSP?

Answer 10

purpuric rash covering limbs and buttocks

Question 11

What are the four classic features of HSP?

Answer 11

purpura
joint pain
abdo pain
renal involvement

Question 12

Which renal condition is associated with HSP?

Answer 12

IgA nephritis

Question 13

what is the management of HSP?

Answer 13

supportive! full recovery within 4-6 weeks (without kidney involvement)

Question 14

what are the complications of HSP?

Answer 14

recurrence 1/3
end stage renal failure 1%

Question 15

name one feature of churg-strauss syndrome= EGPA

Answer 15

lung and skin problems

Question 16

Which vsaculitis presents with elevated eosinophil levels?

Answer 16

churg-strauss syndrome

Question 17

Which vasculitis is associated with epistaxis?

Answer 17

granulomatosis with polyangiits

Question 18

What are the features of granulomatosis with polyangiitis

Answer 18

epistaxis
hearing loss
sinusitis
saddle shaped nose- perforated nasal septum
cough wheeze
haemoptysis
glomerulonephritis

Question 19

polyarteritis nodosa is associated with which infections?

Answer 19

Hep B
Hep C
HIV

Question 20

name two features of kawasaki disease

Answer 20

fever
erythematous rash
bilateral conjunctivitis
erythema and desquamation of palm and soles
strawberry tongue

Question 21

What is a serious complication of kawasaki disease?

Answer 21

coronary artery aneurysm

Question 22

where does takayasu’s arteritis most commonly affect?

Answer 22

aorta

Question 23

Does GCA just affect the temporal artery?

Answer 23

no, affects aorta and its major branches

Question 24

What is the classic distribution of HSP?

Answer 24

purpuric rash over buttocks and thighs

Question 25

What is a classic trigger for HSP?

Answer 25

strep sore throat

Question 26

saddle nose deformity is a feature of which vasculitis?

Answer 26

GPA