Rheumatoid Arthritis Flashcards
List three signs of RA
swan neck
boutonniere
Z thumb
ulnar deviation
Rhematoid nodules
List three extra articular features of RA
Ocular- scleritis, episcleritis
Cardiorespiratory- pleural effusions, pulmonary fibrosis, pulmonary nodules, pericarditis
Splenomegaly
Peripheral neuropathy
Anaemia
Three differentials for RA
polyarticular gout
psoriatic arthritis
OA
SLE
List two blood tests for RA
Rheumatoid factor- non specific
CCP Ab
List two early changes on XR of RA
periartciular osteopenia
soft tissue swelling
List two late changes seen on XR in RA
erosion
joint destruction
subluxation
Why is early referral for RA essential?
Significant joint damage can occur early in the disease
* 93% of patients with <2 years of disease have radiographic abnormalities
How long do DMARDs take to work?
up to 3 months
List three aspects of EULAR classification for RA
Joint involvement
Serology- RF/anti-CCP
Acute phase reactants- CRP + ESR
Duration of symptoms >6 weeks
A score of what for which timeframe of symptoms would fulfil the classification criteria for RA?
> 6 weeks
List three DMARDs
methotrexate
leflunomide
sulfasalazine
hydroxychlorquine
Monitoring for methotrexate?
LFTs FBC
Monitoring for sulfasalazine?
FBC
U+ E
LFT
Which DMARD is safe in pregnancy
sulfasalazine
hydroxychloroquine
Monitoring for hydoxychloroquine?
ocular
