Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CVS Pathology > Vasculitis > Flashcards

Vasculitis Flashcards

1
Q

بسم الله توكلنا عليك وأنت خير الناصرين و انت سميع الدعاء مجيبه فلا تحرمنا من فضلك وأنزل علينا رحماتك تترا يارب العالمين

التهابات الشرايين تشترك جميعها في ؟

A

1-Thickening of the wall
2-Shedding of endothelium forming thrombosis
3-Weakness of wall and Aneurysm formation may rupture forming Hge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

قال معاذ الله إنه ربي أحسن مثواي إنه لا يفلح الظالمون

دور الأجسام المضادة في التهاب الشرايين اذكره

A

1-ممكن تهاجم الخلايا الطلائية علي طول وده في مرض اسمه Kawaski disease
2-ممكن تكون معقدات مناعية من انتيجينات وينشط المكملاتcomplemets وتعمل التهابات
في مرض الذئبة SLE
3-ANCA :Antinuclear cytoplasmic antibody
ودي تضرب في الاوعية الصغيرة وتعمل فيها مشاكل !
______________
Granuloma due to inflammation in wall of large blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Large to small vessel vasculitis (Khalifs describe)

A

Aorta , branches, opthalmic , temporal — Migarane Old males
1-Temporal arteritis ! Giant cell arteritis granulomatous inflammation and giant cell
صداع temp وزغللة في العين opthalmic

2-Takayaso arteritis aorta and its branches to upper limb
radial arteritis pulsless disease granulomatous giant cells
Ischemia in upper limb and giant cell

complications
يطخن الجدار
يعمل جلطات
يعمل توسعات في الشريان

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Giant cell TEMORAL ARETRITID depends on …… immunity

A

T cell mediated immuinty

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Giant cell ARTERITIS affect which arterires ?

A

Temporal and opthalamic samll arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Why it is called giant cell arteritis ?

A

Because it is mechnism is by granuloma formation and giant cells are present

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Takayso desvribe

A

In large to small arteries aortic arch and its branches to the upper limb middle age > granuloma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Mention Medium vessel arteritis .

A

1-Polyarteritis nodosa

2-Kawaski

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

strawberry tongue

appear in ?

A

Kawasaki arteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Polyateritis nodosa mostly appear in and rescpect ?

A

Mostly in kidney cauisng renal arteristsis nodosa and renal failure \
Respect The pulmonary arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The basis of Polayarteriris nodosa is ?

A

The formation of Immune complexes due to Hepatitis B virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The most common pathogen casuing the Polyarteritis nodosa?

A

Hepatitis B virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Describe the gross morph of the PAN .

A

multiple nodules - multiple aneurisms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

describe Microscopic appearance of the PAN .

A

Necrotizing inflammation+ Neutrophils and Fibrosis !

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Clinical picture of the PAN ?

A

Fever +HTN+ abdominal pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Poly Arteritis Nodosa PAN

Description !

A

Multiple arteries mostly renal (not affecting pulmonary
vessels)
Immune complex reaction , may be associated with HBV
infection
gross: multiple nodules - multiple aneurisms
micro: necrotizing inflammation + excess neutrophils →
chronic & fibrosis
Clinical: (Fever + hypertension + abdominal pain)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Arteritis causing MucoCutanuous and LN syndrome involvement

A

Kawasaki

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Kawaski decribe

ركز في اسئلة هوار ولو سألك قله ربنا يعين الجميع ولو قالك يعني ايه قوله معلش مش عايز اقولك لحد بيني وبينه !

A

Medium arteitis

Multiple vessels children

Necrotizing inflammation with Mucocuatnous and LN syndrome
cassuing Strawberry tongue

19
Q

ALL OF small arteritis is characterized by ?>

A

ANCA

20
Q

cANCA appear in ?

A

Wegner granulomatosis .

21
Q

Wegner granulomatosis is chararterizd by

?

A

العجب فقد جمع بين التهابات الشرايين الكبيرة في تكوين الجرانيولوما والتهابات الشرايين المتوسطة في انها
necrotizing

كمان تجرأ علي مالم تتجرأ عليه الالتهابات المتوسطة وهي الرئة والجهاز التنفسي بالإضافة إلي الكلية

22
Q

Wegner granulomatosis وصف

A

respiratory tract & Kidney
– cANCA -
granuloma & necrotizing vasculitis

23
Q

pANCA appar in

A

Charug -straus

24
Q

Charug-Straus disease is characterized by :-

A

Asthma +Eosinophils

25
Q

Chrug straus describe .

A

Affect respiratory aretries forming granuloma and is necrotizing and there is Asthma and eosinopilhs +pANCA

26
Q

ايه الفرق بين
Microscopic polyanigitis
وغيرها ؟

A

انه بعض الحالات مفيش فيها ترسيبات مناعية من ANCA

27
Q

Microscopic polyangitis briefly

A

It is Respiratory and renal disease and is not granulomatous and necrotizing with ANCA and There may be no immune deposits in some cases

28
Q

disease appear in male somkers due to genetic immune and tobacco effect on the endothelium
in small and medium vvessels of limbs

A

it is burger disease
thromboangitis obliterans
segemtnal inflammation and necrosis
thrombosis gangrerne

29
Q

Complications of Burger’s disease

A

Caludications تشنجات في عضلات الساق لنقص التروية
trophic ulcer
gangrene

30
Q

Complications of Renayd disease mention

A

Cyanosis of
finger

nose

ear

31
Q

Renayd disease appear mostly in ?

A

Females due to cold and stress and emotions

Mostly in small arteries

32
Q

Causes of Renayd disease ?

A

1ry due to Vasospasm due to cold and emotions

2ry to DISEASE SLE Burger’s disease

33
Q

Mechanism of burger’s diease ?

A 
It is due to granulomatus inflammation in the veins and arteris and nervers causing
 thrombosis 
Microabscesses 
Fibrosis and 
aneurysm  .
34
Q

SVC syndrome mean ?

A

This occure due to obstruction of the SVC due to ?
Lung carcinoma or Mediastinal lymphoma
this lead to congestion and cyanosis of head and upper limbs

35
Q

IVC Syndrome mean

A

this obstruction of the IVC due to TUMORS OR enlarged LN
and this leads to LL and Renal congestion + proteinuria and
dilated abdominal veins

36
Q

Lymphangitis mean ?

A

It is inflammed lymph vessesl due to infection filaria or radiation appearing as Red streaks and causing obstruction leading to lymphedema

suppurative or tb

37
Q

Chylus effusion defintion .

A

it is effusiion of milky lymph from the lymphatic vessels due to its obsetcuton or rupture into the serous sacs

38
Q

Congenital Vascular disease :

A

AV SHUNT
Berry aneurysm
Fibromusclar dysplasia
وهو استبدال الجزء العضلي في جدار الشريان بنسيج ليفي
thick wall of large and medium sized arteries

39
Q

Monckberge disease >

A

it is senile idiopathic disease
hyalinosis and thickening and dystrophic calcification and ossification of ( M)edia of
(M)usclar (M)deium sized artery like feomral discoverd by (M)onckeberge

مزودتش نسيج جديد بس عملية استبدال

40
Q

Monckeberge is asymptomatic due to ?

A

No Narrowing of the Wall of the blood vessel

41
Q

الحــمــدلله الذي أنزل علي عبده الكتاب لم يجعل له عوجا !

تبارك الذي نزل الفرقان علي عبده ليكون للعالمين نذيرا !

A
42
Q

pathogensis of vasculitis

A

• Immunological
o Immune complex type III hypersenset.(e.g. SLE, PAN,
drug)
o Anti-neutrophil cytoplasmic Ab ANCAs (e.g. Wegener)
o Anti endothelial Ab (e.g. Kawasaki)
• Infections
o Direct by organism
o Indirect → immune mediated reaction
• Other causes (e.g. radiation, Trauma, Chemicals)

43
Q

Complications: of vasculitis

A

Ischemia –
Thrombosis -
Ruptured vessels →
hemorrhage

CVS Pathology (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions