Vasculature Flashcards

0
Q

Veins

A

Carry blood to the heart very slim compared to arteries

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1
Q

Arteries

A

Carry blood away from the heart very thick compared to veins

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2
Q

Capillaries

A

Exchange I vessels

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3
Q

Adult humans have ___ miles of blood vessles

A

60,000 miles

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4
Q
%of blood in each system
Pulmonary circulation
Heart
Systematic circulation
-arteries
-veins
-capillaries
A
Pulmonary:18%
Heart:12%
Circulation:70%
-arteries:13%
-veins:64%
-capillaries:5%
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5
Q

Arterioles

A

Very small branches off the aorta( smallest arteries)
Primary resistance vessels in system
Reduce MAP(93mmHg to 37mmHg)
Concert pulsatilla pressure to constant
Variable distribute cardiac output among organs( vasoconstriction and vasodilatation)

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6
Q

Vasoconstriction

A

Increased contraction of circular smooth muscle in the arteriolar wall which increases resistance and decreases blood flow through

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7
Q

Vasodilatation

A

Decreased contraction of circular smooth muscle in the arteriolar wall which leads to decreased resistance and increased flow of blood

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8
Q

Vasoconstriction triggers

A
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9
Q

Vasodilation triggers

A
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10
Q

Innervation of arterioles

A

Parasympathetic Innervation in penis and clitoris only!!!!
Sympathetic Innervation depending on which adrenergic receptor is expressed a1 receptors- constriction
B2 receptors- dilation

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11
Q

Capillaries

A

The exchange vessel only tunica introns .5 mm thick found every where but… Tendons, ligaments, cartilage, epithelial tissues, cornea and lens

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12
Q

Sphincters on capillaries aloe for the amount of blood circulating through them.

A

Contracted, little blood. Relaxed, full of blood

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13
Q

Bulk flow

A

Balance of inward and outward pressures determines direction of flow. Capillary blood pressure, plasma-colloid osmotic pressure, IFC hydrostatic and colloid osmotic pressure

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14
Q

Exchange in capillaries

A

Bulk flow or passive diffusion down the concentration gradient

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15
Q

Protein filaments in smooth muscle

A

Thick myosin- long
Thin actin- have tropomyosin but not troponin
Intermediate filaments- do not participate directly in contraction, part of cytoskeleton framework

16
Q

What do you do to smooth muscle to activate since there is no troponin?

A

Must be phosphorylation by calcium

17
Q

Poorly developed SR in smooth muscle… Where does ca come from?

A

Ca comes from ECF through voltage gated dihydropyridine receptors

18
Q

Myosin kinase

A

Phosphorylates myosine

19
Q

Myosin phosphatase

A

Dephosphorylates myosin

20
Q

Blood pressure equation

A

CO=HRxSV

BP= COxPR

21
Q

Total blood flow equation

A

Q= DP(pressure gradient)/PR(resistance)

22
Q

Factors that increase total blood

Flow

A

Increase in cardiac output

Vasodilation( less resistance)

23
Q

Factors that decrease total blood flow

A

Decrease in cardiac output

Vasoconstriction( more resistance)

24
Q

Systolic pressure with pressure cuff

A

Pressure at which the sound is first heard when artery is unblocked

25
Q

Diastolic pressure with pressure cuff

A

When sounds disappear. The brachial artery remains open

26
Q

Mean arterial pressure(MAP)

A

MAP= diastolic pressure+pulse pressure/3

Pulse pressure= systolic pressure-diastolic pressure

27
Q

When u work ou you loose blood in…

A

Kidney, abdominal organs, other

28
Q

When you work out the blood increases in…

A

Brain, heart, skin, skeletal muscles

29
Q

Short term blood pressure regulation

A

Neural circuitry

Baroreceptors