Vascular - Venous pathology Flashcards
What are the 2 venous systems taking blood from the lower limbs back to the trunk?
Superficial + deep vv system
Superficial vv system
Medial: long great saphenous vv
Lateral: short saphenous vv
Where does the long great saphenous vv drain into
Into saphenofemoral jct
Where does the short saphenous vv drain into
popliteal vv
What does the deep venous system drain?
The muscle compartment
What does the superficial vv system drain?
Skin + surrounding tissues
Where are the superficial and deep vv systems joined?
Saphenofemoral + saphenopopliteal jct
What comprises the additional communications between the deep + superficial vv systems
Periforating vv
What prevents backflow in the leg vv
valves
Which vv do not have valvves (2)
Vena cava
COmmon iliac vv
What drives vv return to the heart?
Pressure from mm pumps below
_+ inspiration decreasing intrathoracic P
What does vv disease in deep vv lead to?
Deep venous insufficiency
What does vv disease in superficial vv lead to
Simple varicose vv
What are both varicose vv and deep vv insufficiency a result of?
Valvular incompetence
Def varicose vv
Abnormally dilated and lengthened superficial vv
What are the 2 types of varicose vv
Primary (idiopathic)
Secondary
What is the most common type of varicose vv
Primary
M:F 1’ varicose vv
1:2
What are 1’ varicose vv due to
1’ superficial valve defects with familial elements
What do 2’ varicose vv occur 2’ to
Deep vv incompetence
Causes of 2’ varicose vv
Prev DVT
Raised systemic vv P (b/c compression)
Sx of varicose vv (4)
Unsightly
Tired, aching, throbbing legs
Oedema ankles, partic after standing for long periods
Signs of deep vv insufficiency
Are varicose vv usually painful
No
When are varicose vv painful
If thrombophlebitis is present
What is thrombophlebitis
Inflamm of superficial vv due to venous stasis
Why does deep vv insufficiency occur
Valves of deep vv system are incompetent, so calf can’t efficiently return blood to thoracic cavity
What is 1’ deep vv insufficiency due to
Congenital absence valves
What is 2’ deep vv insufficiency due to
DVT –> valvular damage or AVF raising vv pressure
Features deep vv insufficiency (8)
Limb aching/discomfort Oedema lower leg Superficial varicose vv Haemosiderin deposition Eczema over pigmented area --> pruritis Atrophic blanche Lipodermatosclerosis Ulceration
Ix deep vv insufficiency
Duplex sonography
Or venography
Different Ix for diagnosing vv diseaase
Hand held doppler
Duplex scanning - using B mode
Venography
Trendelenberg
What does hand-held doppler do
ID reflux at saphenofemoral/saphenopoliteal jct
What does dupplex scanning (b mode) do
Diagnose valvular and perforating vv incompotence as well as large vv occlusion
How does venography work
Tourniquet placed around ankle to occlude superficial vv, then contrast injected into foot
Tx indications varicose vv (4)
Grossly dilated/ Sx varicosities
Haemorrhage
Concomitant deep vv insuffiency
Incompetent perforator vv
Tx options varicose vv (5)
1 - lifestyle advice 2 - graded stocking 3 - endothermal ablation - Tx of choice 4 - Sclerotherapy 5 - surgery
What lifestyle advice can you give for Mx varicose vv (3)
Avoid prolonged standing
Exercise regularly
Lose W
What is the gold standard Mx of varicose vv
Surgery
Complications of varicose vv
Haemorrhage (from minor trauma)
Phelbitis
Sx of phlebitis
VV becomes harder + tender + erythema + systemic upset
Most common sites of DVT (5)
Anterior tibiial Posterior tibial Perineal Superior femoral Popliteal vv
RF DVT (9)
Age Immobility Pregnancy OCP Malignancy Obesity Surgery Prev DVT
CF DVT (7)
Mostly silent Calf tenderness + firmness Oedema Erythema + calor Distention superficial vv Superficial thrombophlebitis Homans sign
What is Homans sign + why doesn’t it be tested
Pain on dorsiflexion ankle
Shouldn’t be tested in case of dislodging
How can iliofemoral thrombosis PS
Severe pain
PS PE (3)
Sudden onset unexplained dyspnoea
Pleuritic chest pain
Haemoptysis
Ix DVT
D-dimer
Compression USS
Thrombophilia screen
Is D-dimer sensitive or specific to DVT’s
Sensitive
Other conditions –> raised D-DImer
Infection
Pregnancy
Malignancy
Post0op
Preventing DVT’s post op (4)
STOP COCP 4w pre-op
Mobilise ASAP
If immobile - herapinize pt
Support hosiery
Tx of proven DVT
LMWH - then stop when INR 2-3
Heparin
How long to take WARFARIN for - provoked DVT
3m
How long to take Warfarin for - unprovoked DVT
6m
How long to take Warfarin for - rec DVT/known thrombophilia
LIfe
DDx - pt who ps w/ bilateral leg swelling
Lymphoedema Cellulitis Varicose vv Phlebitis Acute aa ischaemia HF Hyponatraemia
Chronic vv insufficiency - VVV LAPS
Varicose vv Venous ulcers Venous stars Lipodermatosclerosis Atrophy blanche Pitting oedema Scars
Venous ulcer appearance
Shallow with irregular borders + granulating base
Esp over medial malleolus
Arterial ulcer appearance
Often small deep lesions with well defined borders and a necrotic base
Neuropathic ulcer appearance
Punched out appearance, most commonly on site of P in foot (glove + stocking distribution)
What is cellulitis
Infection of skin + underlying soft tissue
What are PE’s usually caused by?
DVT’s in legs
PS PE
Sudden onset breathlessness
Pleuritic pain
Haemoptyisis
How many days post surgical do PE’s tend to occur
c day 10
Def massive PE (5%)
> 60% pulmonary circulation is blocked
Outcome of massive PE
Rapid CV collapse
Def major PE (10% )
Middle sized pulm aa is blocked
Sx Major PE (3)
Breathlessness
Pleuritic chest pain
Haemoptysis
Def minor PE (85%)
Small peripheral vessels are blocked
What is a premonitory embolus
Massive PE may ensue following a minor PE
Signs PE (3)
DVT
Raised JVP
Cyanosis if embolus is large
Ix - suspected PE (9)
FBC, U+E, clotting, D-dimer ABG CXR ECG Echo CTPA
CXR findings PE (3)
Often norm
Or dilated pulm aa
Wedge shape opacities
ECG findings PE
Tachy C
RBBB
RV strain - SI, QIII, TIII = rare
What is SI, QIII, TIII
Large S wave lead I
Q wave lead III
T wave inversion III
What is the gold standard Ix PE
CTPA
Mx massive PE
A-E IV morphine + anti-emetic LMWH If SBP >90 --> Warfarin If <90 - start vasopressors first
Def lymphoedema
Swelling which results from an increased quantity of fl in the interstitial space of soft tissues, due to failure of lymphatic drainage
Congenital cause of primary lymphodema?
Milroys - congen abnormality of lymphatic vessels
2’ causes of lymphoedema
B/c obstruction of lymphatic vessels Filaria infection Repeated cellulitis Malignancy Post op
What is Stemmer’s sign
Pinch + lift skin on 2nd toe to establish presence of lymphoedema
Ix lymphoedema
Lymphoscintography
Mx lymphoedema
Elevation
Compression stockings
Massage
Risks of angiography (5)
Contrast reaction Haematoma Pseudoaneurysm AVF formation Aa occlusion