Vascular Diseases 2025 (Exam 4) Flashcards

1
Q

3 main arterial pathologies

A

Aneurysms
Dissections
Occlusions

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2
Q

Peripheral arteries are more likely to be effected by which main pathology?

A

Occlusions

POA

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3
Q

When is surgery indicated for aortic aneurysms?

A

Surgery is indicated at > 5.5 cm in diameter
Growth > 10 mm/year
Family history of dissection

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4
Q

Which diagnostic is fastest/safest for suspected aortic dissection with aortic anurysm if unstable?

A

Doppler echocardiogram

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5
Q

Symptoms of aortic dissection

A

Severe sharp pain in posterior chest or back

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6
Q

Ascending aortic Dissections are what classification?

A

Stanford A & Debakey 1 & 2

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7
Q

Ascending aortic aneurysms are what classification?

A

None.
Only Dissections have classifications

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8
Q

Goals for medically managing aortic aneurysm aim to

A

↓expansion rate

Manage BP, cholesterol, stop smoking

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9
Q

What temp and time for circulatory arrest is tolerated by most patients for ascending dissection repair?

A

15-18 C for 30-40 minutes

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10
Q

What is a major complication associated with aortic arch replacement surgery?

A

Neurological deficit (3-18%)

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11
Q

What is medical therapy for Stanford B (Descending) dissection? (3)

A
  1. Arterial monitoring of SBP and UOP
  2. Drugs to decrease BP
  3. Drugs to decrease force of LV contraction
    (BB, Cardene, SNP)
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12
Q

What type of dissection is catastrophic and emergent, requiring emergent surgical intervention

A

Ascending aortic dissection (Stanford A, Debakey 1 & 2)

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13
Q

Surgery is indicated for pts with ____ dissection with signs of ____ ____. These signs include:

A

Surgery is indicated for pts with Type B dissection with signs of impending rupture.

Persistant pain
hypotension
left-sided hemothorax

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14
Q

Signs of impending rupture with Descending aortic arch dissection:

If seen what is done?

A

Posterior pain
hypotension
hemothorax

Surgical treatment

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15
Q

Aortic Dissection is more commonly seen in who?

A

Men
Women in the 3rd trimester of pregnancy

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16
Q

What are the triad of symptoms seen in aortic aneurysm rupture in about 50% of cases?

A

Hypotension
Back pain
Pulsatile abdominal mass

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17
Q

Most abdominal aortic aneurysms rupture into which space?

A

Left Retroperitoneum

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18
Q

What should be done if retroperitoneal tamponade occurs?

A

Euvolemic resuscitation should be delayed until the rupture is controlled surgically.

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19
Q

What could happen if volume resuscitation is given to a pt with a retroperitoneal tamponade?

A

Further bleeding
hypotension
death

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20
Q

What are 4 primary causes of mortality related to surgeries of the thoracic aorta?

A
  • MI
  • Respiratory failure
  • Renal failure
  • Stroke
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21
Q

What 2 things may preclude a patient from aortic resection?

A

Low FEV1 and Renal failure (bad outcomes)

22
Q

What is a predictor of post aortic surgery respiratory failure?
What interventions could help to avoid this?

A

Smoking/COPD
- Consider bronchodilators, ABX, and chest physiotherapy

23
Q

What is the most significant indicator of post-aortic surgery renal failure?
How can this be avoided?

A

Preop Renal Dysfunction

Preoperatively hydrate
Avoid hypovolemia & low CO
Avoid nephrotoxins

24
Q

The ASA perfuses the ______ ____ of the spinal cord

A

Anterior 2/3

25
ASA ischemia leads to: (3)
1. Loss of function below the infarct 2. Diminished pain and temperature sensation below the infarct 3. Autonomic Dysfunction - (Hypotension and bowel/bladder problems)
26
What are 4 causes of ASA syndrome?
1. Aortic aneurysm 2. Aortic Dissection 3. Atherosclerosis 4. Trauma
27
AHA recommends TPA within ____ hrs of symptom onset of a CVA
4.5 hrs of symptom onset
28
CEA is indicated for carotid stenosis when lumen diameter is _____ mm or > _____ % blockage
CEA when diameter 1.5 mm or > 70% blockage (benefits outweigh risks)
29
CEA preop eval should include:
Neurologic evaluation: **establish preop deficits** Post-CVA weakness aphasia disorientation
30
CPP =
MAP - ICP
31
Cerebral O2 consumption is effected by:
1. Temperature 2. Depth of anesthesia
32
Peripheral artery disease (compromised blood flow to extremities) is defined by ankle-brachial index (ABI) < ___?
ABI < 0.9
33
PAD pt. have relief when doing what?
When hanging LE over the side of the bed (increased hydrostatic pressure)
34
Common causes of acute peripheral artery occlusion are (2)
1. LA thrombus d/t A-Fib 2. LV Thrombus due to cardiomyopathy after MI
35
Sublcavian steal syndrome is characterized by:
Occluded Subclavian artery proximal to the vertebral artery
36
What does SC steal syndrome cause?
Vertebral artery blood flow to be diverted away from brain stem
37
If you have right SC steal syndrome, the ____ arm will have SBP ____ mmHg lower
Right arm; 20 mmHg lower
38
A symptom of SC steal syndrome:
Bruit heard over SCA
39
Raynaud's Phenomenon may appear with ____
CREST Syndrome **(scleroderma subtype)** Scleroderma and vasculitis
40
What is Virchow’s triad?
3 Factors that predispose pts to venous thrombosis (VHD) -Venous stasis -Hypercoagulability -Disrupted vascular endothelium
41
Risk factors for DVT? (5)
1. Age > 40 2. Surgery over 1 hour 3. Cancer 4. Ortho surgery on pelvis and LE 5. Abdominal surgery
42
What are prophylactic intervention for DVT?
1. compression stocking 2. SCD 3. SQ heparin 2-3x per day
43
What are LMWH advantages over unfractionated heparin? (4)
1. Longer half-life 2. More predictable dose-response 3. No serial aPTT assessment 4. Less bleeding risk
44
Large-artery Vasculitis includes
- Takayasu Arteritis - in neck - Temporal (giant cell) Arteritis - head and neck
45
Medium-small artery Vasculitis includes
- **Thromboangiitis Obliterans** --> BUERGER - Wegener Granulomatosis - **Polyarteritis Nodosa**
46
Treatment for Temporal arteritis
Corticosteroids for visual symptoms and to prevent blindness (might need stress-dosing)
47
Thromboangiitis Obliterans is an autoimmune response triggered by ____ with ____ use being the most predisposing factor in men < 45 years
Nicotine; **Tobacco**
48
5 diagnostic criteria for Thromboangiitis Obliterans
1. Hx of smoking 2. Onset before 50 3. Infrapopliteal arterial occlusive disease 4. Upper limb involvement 5. Absence of risk factors for atherosclerosis (outside of tobacco)
49
S/s of Thromboangiitis Obliterans (4)
- forearm, calf, foot claudication - Ischemia of hands & feet - Ulceration and skin necrosis - **Raynaud’s is commonly seen**
50
Inflammation of the small/medium vessels leading to glomerulonephritis, myocardial ischemia, peripheral neuropathy and seizures is?
Polyarteritis Nodosa
51
What is the primary cause of death in Polyarteritis Nodosa
Renal failure (HTN results in renal disease)
52
Contraindications for ablation of chronic venous disease (5)
1. **Pregnancy** 2. Thrombosis 3. PAD 4. Limited mobility 5. Congenital venous abnormalities